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Showing content from https://www.ncbi.nlm.nih.gov/pubmed/30241646 below:

The Role of Genetics in Pancreatitis

Review

Affiliations

• ¹ Department of Internal Medicine, Columbia University Medical Center, 630 West 168 Street, New York, NY, 10032, USA.
• ² Division of Digestive and Liver Diseases, Columbia University Medical Center, 630 West 168 Street, New York, NY, 10032, USA.
• ³ Division of Digestive and Liver Diseases, Columbia University Medical Center, Herbert Irving Comprehensive Cancer Center, 161 Fort Washington Avenue, Suite 862, New York, NY 10032, USA. Electronic address: fk18@columbia.edu.

• PMID: 30241646
• DOI: 10.1016/j.giec.2018.06.001

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Review

Aws Hasan et al. Gastrointest Endosc Clin N Am. 2018 Oct.

• ¹ Department of Internal Medicine, Columbia University Medical Center, 630 West 168 Street, New York, NY, 10032, USA.
• ² Division of Digestive and Liver Diseases, Columbia University Medical Center, 630 West 168 Street, New York, NY, 10032, USA.
• ³ Division of Digestive and Liver Diseases, Columbia University Medical Center, Herbert Irving Comprehensive Cancer Center, 161 Fort Washington Avenue, Suite 862, New York, NY 10032, USA. Electronic address: fk18@columbia.edu.

• PMID: 30241646
• DOI: 10.1016/j.giec.2018.06.001

Item in Clipboard

Individuals with acute recurrent and chronic pancreatitis may have an inherited predisposition to the development of the disease. Pancreatitis in the setting of a significant family history of the disease can be classified as hereditary or familial pancreatitis. In this article, the authors closely examine the specific genes implicated in pancreatitis, investigate the role of genetic testing for diagnosis, and describe the impact of genetic testing results on clinical management.

Keywords: CFTR; Familial pancreatitis; Genetic evaluation; Genetic variants associated with pancreatitis; Hereditary pancreatitis; PRSS1; SPINK1.

Copyright © 2018 Elsevier Inc. All rights reserved.

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• CFTR, SPINK1, PRSS1, and CTRC mutations are not associated with pancreatic cancer in German patients.

  Schubert S, Traub F, Brakensiek K, von Kopylow K, Marohn B, Maelzer M, Gaedcke J, Kreipe H, Stuhrmann M. Schubert S, et al. Pancreas. 2014 Oct;43(7):1078-82. doi: 10.1097/MPA.0000000000000166. Pancreas. 2014. PMID: 25003218

• Screening of pancreatic cancer: Target population, optimal timing and how?

  Waleleng BJ, Adiwinata R, Wenas NT, Haroen H, Rotty L, Gosal F, Rotty L, Winarta J, Waleleng A, Simadibrata M. Waleleng BJ, et al. Ann Med Surg (Lond). 2022 Nov 5;84:104814. doi: 10.1016/j.amsu.2022.104814. eCollection 2022 Dec. Ann Med Surg (Lond). 2022. PMID: 36582884 Free PMC article. Review.

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