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Showing content from https://www.echa.europa.eu/candidate-list-table below:

Candidate List of substances of very high concern for Authorisation

(published in accordance with Article 59(10) of the REACH Regulation)

The List does not contain any Substances.

Substance name EC No. CAS No. Date of inclusion tetra(sodium/potassium) 7-[(E)-{2-acetamido-4-[(E)-(4-{[4-chloro-6-({2-[(4-fluoro-6-{[4-(vinylsulfonyl)phenyl]amino}-1,3,5-triazine-2-yl)amino]propyl}amino)-1,3,5-triazine-2-yl]amino}-5-sulfonato-1-naphthyl)diazenyl]-5-methoxyphenyl}diazenyl]-1,3,6-naphthalenetrisulfonate (Reactive Brown 51)

substance having a complex composition with <80% of the above constituents and other reaction side products

466-490-7

25-Jun-2025

Toxic for reproduction (Article 57c)

D(2025)4165-DC Details decamethyltetrasiloxane

205-491-7

141-62-8

25-Jun-2025

vPvB (Article 57e)

D(2025)4165-DC Details 1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane

241-867-7

17928-28-8

25-Jun-2025

vPvB (Article 57e)

D(2025)4165-DC Details reaction mass of: triphenylthiophosphate and tertiary butylated phenyl derivatives

421-820-9

192268-65-8

21-Jan-2025

PBT (Article 57d)

D(2024)7663-DC Details Perfluamine

206-420-2

338-83-0

21-Jan-2025

vPvB (Article 57e)

D(2024)7663-DC Details Octamethyltrisiloxane

203-497-4

107-51-7

21-Jan-2025

vPvB (Article 57e)

D(2024)7663-DC Details O,O,O-triphenyl phosphorothioate

209-909-9

597-82-0

21-Jan-2025

PBT (Article 57d)

D(2024)7663-DC Details 6-[(C10-C13)-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid

701-118-1

2156592-54-8

21-Jan-2025

Toxic for reproduction (Article 57c)

D(2024)7663-DC Details Triphenyl phosphate

204-112-2

115-86-6

07-Nov-2024

Endocrine disrupting properties (Article 57(f) - environment)

D(2024)6225-DC Details Bis(α,α-dimethylbenzyl) peroxide

201-279-3

80-43-3

27-Jun-2024

Toxic for reproduction (Article 57c)

D(2024)4144-DC Details Oligomerisation and alkylation reaction products of 2-phenylpropene and phenol

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Phenol, methylstyrenated EC No.: 270-966-8 | CAS No.: 68512-30-1

700-960-7

23-Jan-2024

vPvB (Article 57e)

D(2023)8585-DC Details Bumetrizole (UV-326)

223-445-4

3896-11-5

23-Jan-2024

vPvB (Article 57e)

D(2023)8585-DC Details 2-(dimethylamino)-2-[(4-methylphenyl)methyl]-1-[4-(morpholin-4-yl)phenyl]butan-1-one

438-340-0

119344-86-4

23-Jan-2024

Toxic for reproduction (Article 57c)

D(2023)8585-DC Details 2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol (UV-329)

221-573-5

3147-75-9

23-Jan-2024

vPvB (Article 57e)

D(2023)8585-DC Details 2,4,6-tri-tert-butylphenol

211-989-5

732-26-3

23-Jan-2024

Toxic for reproduction (Article 57c)

PBT (Article 57d)

D(2023)8585-DC Details diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide

278-355-8

75980-60-8

14-Jun-2023

Toxic for reproduction (Article 57c)

D(2023)3788-DC Details bis(4-chlorophenyl) sulphone

201-247-9

80-07-9

14-Jun-2023

vPvB (Article 57e)

D(2023)3788-DC Details reaction mass of 2,2,3,3,5,5,6,6-octafluoro-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)morpholine and 2,2,3,3,5,5,6,6-octafluoro-4-(heptafluoropropyl)morpholine

473-390-7

17-Jan-2023

vPvB (Article 57e)

D(2022)9120-DC Details Perfluoroheptanoic acid and its salts

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potassium perfluoroheptanoate EC No.: - | CAS No.: 21049-36-5 Perfluoroheptanoic acid EC No.: 206-798-9 | CAS No.: 375-85-9 Sodium perfluoroheptanoate EC No.: 243-518-4 | CAS No.: 20109-59-5 Ammonium perfluoroheptanoate EC No.: 228-098-2 | CAS No.: 6130-43-4

17-Jan-2023

Toxic for reproduction (Article 57c)

PBT (Article 57d)

vPvB (Article 57e)

Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health)

Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)

D(2022)9120-DC Details Melamine

203-615-4

108-78-1

17-Jan-2023

Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health)

Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)

D(2022)9120-DC Details Isobutyl 4-hydroxybenzoate

224-208-8

4247-02-3

17-Jan-2023

Endocrine disrupting properties (Article 57(f) - human health)

D(2022)9120-DC Details bis(2-ethylhexyl) tetrabromophthalate covering any of the individual isomers and/or combinations thereof

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Bis(2-ethylhexyl) tetrabromophthalate EC No.: 247-426-5 | CAS No.: 26040-51-7

17-Jan-2023

vPvB (Article 57e)

D(2022)9120-DC Details Barium diboron tetraoxide

237-222-4

13701-59-2

17-Jan-2023

Toxic for reproduction (Article 57c)

D(2022)9120-DC Details 4,4'-sulphonyldiphenol

201-250-5

80-09-1

17-Jan-2023

Toxic for reproduction (Article 57c)

Endocrine disrupting properties (Article 57(f) - environment)

Endocrine disrupting properties (Article 57(f) - human health)

D(2022)9120-DC Details 2,2',6,6'-tetrabromo-4,4'-isopropylidenediphenol

201-236-9

79-94-7

17-Jan-2023

Carcinogenic (Article 57a)

D(2022)9120-DC Details 1,1'-[ethane-1,2-diylbisoxy]bis[2,4,6-tribromobenzene]

253-692-3

37853-59-1

17-Jan-2023

vPvB (Article 57e)

D(2022)9120-DC Details N-(hydroxymethyl)acrylamide

213-103-2

924-42-5

10-Jun-2022

Carcinogenic (Article 57a)

Mutagenic (Article 57b)

D(2022)4187-DC Details tris(2-methoxyethoxy)vinylsilane

213-934-0

1067-53-4

17-Jan-2022

Toxic for reproduction (Article 57c)

D(2021)10043-DC Details S-(tricyclo(5.2.1.0'2,6)deca-3-en-8(or 9)-yl O-(isopropyl or isobutyl or 2-ethylhexyl) O-(isopropyl or isobutyl or 2-ethylhexyl) phosphorodithioate

X4261

401-850-9

255881-94-8

17-Jan-2022

PBT (Article 57d)

D(2021)10043-DC Details 6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol

204-327-1

119-47-1

17-Jan-2022

Toxic for reproduction (Article 57c)

D(2021)10043-DC Details (±)-1,7,7-trimethyl-3-[(4-methylphenyl)methylene]bicyclo[2.2.1]heptan-2-one covering any of the individual isomers and/or combinations thereof (4-MBC)

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(±)-1,7,7-trimethyl-3-[(4-methylphenyl)methylene]bicyclo[2.2.1]heptan-2-one EC No.: 253-242-6 | CAS No.: 36861-47-9 (3E)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 1782069-81-1 (1R,3E,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 95342-41-9 (1S,3E,4R)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 852541-30-1 (1R,3Z,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 852541-21-0 (1R,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 741687-98-9 (1S,3Z,4R)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 852541-25-4

17-Jan-2022

Endocrine disrupting properties (Article 57(f) - human health)

D(2021)10043-DC Details Phenol, alkylation products (mainly in para position) with C12-rich branched alkyl chains from oligomerisation, covering any individual isomers and/ or combinations thereof (PDDP)

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4-isododecylphenol EC No.: - | CAS No.: 27459-10-5 Phenol, tetrapropylene- EC No.: - | CAS No.: 57427-55-1 Phenol, 4-dodecyl, branched EC No.: - | CAS No.: 210555-94-5 Phenol, (tetrapropenyl) derivatives EC No.: - | CAS No.: 74499-35-7 Phenol, 4-isododecyl- EC No.: - | CAS No.: 27147-75-7 Phenol, dodecyl-, branched EC No.: 310-154-3 | CAS No.: 121158-58-5

08-Jul-2021

Toxic for reproduction (Article 57c)

Endocrine disrupting properties (Article 57(f) - environment)

Endocrine disrupting properties (Article 57(f) - human health)

D(2021)4569-DC Details orthoboric acid, sodium salt

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Boric acid, sodium salt EC No.: 215-604-1 | CAS No.: 1333-73-9 Orthoboric acid, sodium salt EC No.: 237-560-2 | CAS No.: 13840-56-7 boric acid (H3BO3), sodium salt, hydrate EC No.: - | CAS No.: 25747-83-5 boric acid (H3BO3), sodium salt (1:1) EC No.: - | CAS No.: 14890-53-0 Boric acid (H3BO3), disodium salt EC No.: - | CAS No.: 22454-04-2 Trisodium orthoborate EC No.: 238-253-6 | CAS No.: 14312-40-4

08-Jul-2021

Toxic for reproduction (Article 57c)

D(2021)4569-DC Details Medium-chain chlorinated paraffins (MCCP)

UVCB substances consisting of more than or equal to 80% linear chloroalkanes with carbon chain lengths within the range from C14 to C17

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Alkanes, C14-17, chloro EC No.: 287-477-0 | CAS No.: 85535-85-9 Tetradecane, chloro derivs. EC No.: - | CAS No.: 198840-65-2 Alkanes, C14-16, chloro EC No.: - | CAS No.: 1372804-76-6 di-, tri- and tetrachlorotetradecane EC No.: - | CAS No.: -

08-Jul-2021

PBT (Article 57d)

vPvB (Article 57e)

D(2021)4569-DC Details glutaral

203-856-5

111-30-8

08-Jul-2021

Respiratory sensitising properties (Article 57(f) - human health)

D(2021)4569-DC Details 4,4'-(1-methylpropylidene)bisphenol

201-025-1

77-40-7

08-Jul-2021