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Vaccines for Moderately to Severely Immunocompromised People | COVID-19

Who is moderately or severely immunocompromised?

You can be immunocompromised (have a weakened immune system) because of a medical condition or if you received medications or treatments that suppress your immune system.

You can self-confirm if you are moderately or severely immunocompromised. This means you do NOT need documentation to receive a COVID-19 vaccination you are eligible for.

Vaccine recommendations for people who are moderately or severely immunocompromised

Certain vaccine brands are recommended for specific age groups. Learn more.

Initial COVID-19 vaccination series

If you have never had a COVID-19 vaccine, you start with an initial multi-dose series, given one time. The number of doses depends on your age and the vaccine brand you get.

Already completed initial series Never received a COVID-19 vaccine Started but did not complete initial series

Note: For all age groups, it is recommended to use the same brand of COVID-19 vaccine doses for the initial series. In some situations, a COVID-19 vaccine from a different brand may be used. Talk to your healthcare provider for more information.

*While it is the recommended to get 2024-2025 COVID-19 vaccine doses 6 months apart, the minimum time is 2 months apart, which allows flexibility to get the second dose prior to typical COVID-19 surges, travel, life events, and healthcare visits.

Getting additional doses

After talking with a healthcare provider, people who are moderately or severely immunocompromised may get more doses (in addition to the ones described above) at least 2 months after their last dose of 2024–2025 COVID-19 vaccine. For children ages 6 months–4 years, these doses should be the same vaccine brand.

Get more details about these recommendations.

People who recently had COVID-19

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