This is the released version of wppi; for the devel version, see wppi.
Weighting protein-protein interactionsBioconductor version: Release (3.21)
Protein-protein interaction data is essential for omics data analysis and modeling. Database knowledge is general, not specific for cell type, physiological condition or any other context determining which connections are functional and contribute to the signaling. Functional annotations such as Gene Ontology and Human Phenotype Ontology might help to evaluate the relevance of interactions. This package predicts functional relevance of protein-protein interactions based on functional annotations such as Human Protein Ontology and Gene Ontology, and prioritizes genes based on network topology, functional scores and a path search algorithm.
Author: Ana Galhoz [cre, aut] ORCID: 0000-0001-7402-5292 , Denes Turei [aut] ORCID: 0000-0002-7249-9379 , Michael P. Menden [aut] ORCID: 0000-0003-0267-5792 , Albert Krewinkel [ctb, cph] (pagebreak Lua filter)
Maintainer: Ana Galhoz <ana.galhoz at helmholtz-muenchen.de>
Citation (from within R, entercitation("wppi")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("wppi")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("wppi")Follow Installation instructions to use this package in your R session.
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