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Bioconductor - terapadog

terapadog

This is the released version of terapadog; for the devel version, see terapadog.

Translational Efficiency Regulation Analysis using the PADOG Method

Bioconductor version: Release (3.21)

This package performs a Gene Set Analysis with the approach adopted by PADOG on the genes that are reported as translationally regulated (ie. exhibit a significant change in TE) by the DeltaTE package. It can be used on its own to see the impact of translation regulation on gene sets, but it is also integrated as an additional analysis method within ReactomeGSA, where results are further contextualised in terms of pathways and directionality of the change.

Author: Gionmattia Carancini [cre, aut] ORCID: 0000-0001-7936-4883

Maintainer: Gionmattia Carancini <gionmattia at gmail.com>

Citation (from within R, enter citation("terapadog")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("terapadog")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("terapadog")
terapadog: Translational Efficiency Regulation Analysis & Pathway Analysis with Down-weighting of Overlapping Genes HTML R Script Reference Manual PDF Details biocViews GeneRegulation, GeneSetEnrichment, Reactome, RiboSeq, Software, Transcriptomics Version 1.0.0 In Bioconductor since BioC 3.21 (R-4.5) (< 6 months) License GPL-2 Depends Imports DESeq2, KEGGREST, stats, utils, dplyr, plotly, htmlwidgets, biomaRt, methods System Requirements URL https://github.com/Gionmattia/terapadog Bug Reports https://github.com/Gionmattia/terapadog/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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