This is the released version of tadar; for the devel version, see tadar.
Transcriptome Analysis of Differential Allelic RepresentationBioconductor version: Release (3.21)
This package provides functions to standardise the analysis of Differential Allelic Representation (DAR). DAR compromises the integrity of Differential Expression analysis results as it can bias expression, influencing the classification of genes (or transcripts) as being differentially expressed. DAR analysis results in an easy-to-interpret value between 0 and 1 for each genetic feature of interest, where 0 represents identical allelic representation and 1 represents complete diversity. This metric can be used to identify features prone to false-positive calls in Differential Expression analysis, and can be leveraged with statistical methods to alleviate the impact of such artefacts on RNA-seq data.
Author: Lachlan Baer [aut, cre] ORCID: 0000-0001-5213-3401 , Stevie Pederson [aut] ORCID: 0000-0001-8197-3303
Maintainer: Lachlan Baer <baerlachlan at gmail.com>
Citation (from within R, entercitation("tadar")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("tadar")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("tadar")Follow Installation instructions to use this package in your R session.
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