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Bioconductor - scDD

scDD

This is the released version of scDD; for the devel version, see scDD.

Mixture modeling of single-cell RNA-seq data to identify genes with differential distributions

Bioconductor version: Release (3.21)

This package implements a method to analyze single-cell RNA- seq Data utilizing flexible Dirichlet Process mixture models. Genes with differential distributions of expression are classified into several interesting patterns of differences between two conditions. The package also includes functions for simulating data with these patterns from negative binomial distributions.

Author: Keegan Korthauer [cre, aut] ORCID: 0000-0002-4565-1654

Maintainer: Keegan Korthauer <keegan at stat.ubc.ca>

Citation (from within R, enter citation("scDD")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("scDD")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("scDD")
Details biocViews Bayesian, Clustering, DifferentialExpression, ImmunoOncology, MultipleComparison, RNASeq, SingleCell, Software, Visualization Version 1.32.0 In Bioconductor since BioC 3.5 (R-3.4) (8 years) License GPL-2 Depends R (>= 3.5.0) Imports fields, mclust, BiocParallel, outliers, ggplot2, EBSeq, arm, SingleCellExperiment, SummarizedExperiment, grDevices, graphics, stats, S4Vectors, scran System Requirements URL https://github.com/kdkorthauer/scDD Bug Reports https://github.com/kdkorthauer/scDD/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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