This is the released version of methylSig; for the devel version, see methylSig.
MethylSig: Differential Methylation Testing for WGBS and RRBS DataBioconductor version: Release (3.21)
MethylSig is a package for testing for differentially methylated cytosines (DMCs) or regions (DMRs) in whole-genome bisulfite sequencing (WGBS) or reduced representation bisulfite sequencing (RRBS) experiments. MethylSig uses a beta binomial model to test for significant differences between groups of samples. Several options exist for either site-specific or sliding window tests, and variance estimation.
Author: Yongseok Park [aut], Raymond G. Cavalcante [aut, cre]
Maintainer: Raymond G. Cavalcante <rcavalca at umich.edu>
Citation (from within R, entercitation("methylSig")
): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("methylSig")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("methylSig")
Details biocViews DNAMethylation, DifferentialMethylation, Epigenetics, MethylSeq, Regression, Software Version 1.20.0 In Bioconductor since BioC 3.11 (R-4.0) (5 years) License GPL-3 Depends R (>= 3.6) Imports bsseq, DelayedArray, DelayedMatrixStats, DSS, IRanges, GenomeInfoDb, GenomicRanges, methods, parallel, stats, S4Vectors System Requirements URL Bug Reports https://github.com/sartorlab/methylSig/issues See More Package Archives
Follow Installation instructions to use this package in your R session.
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