This is the released version of magrene; for the devel version, see magrene.
Motif Analysis In Gene Regulatory NetworksBioconductor version: Release (3.21)
magrene allows the identification and analysis of graph motifs in (duplicated) gene regulatory networks (GRNs), including lambda, V, PPI V, delta, and bifan motifs. GRNs can be tested for motif enrichment by comparing motif frequencies to a null distribution generated from degree-preserving simulated GRNs. Motif frequencies can be analyzed in the context of gene duplications to explore the impact of small-scale and whole-genome duplications on gene regulatory networks. Finally, users can calculate interaction similarity for gene pairs based on the Sorensen-Dice similarity index.
Author: FabrÃcio Almeida-Silva [aut, cre] ORCID: 0000-0002-5314-2964 , Yves Van de Peer [aut] ORCID: 0000-0003-4327-3730
Maintainer: FabrÃcio Almeida-Silva <fabricio_almeidasilva at hotmail.com>
Citation (from within R, entercitation("magrene")
): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("magrene")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("magrene")
Details See More Package Archives
Follow Installation instructions to use this package in your R session.
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