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Bioconductor - gemini

gemini

This is the released version of gemini; for the devel version, see gemini.

GEMINI: Variational inference approach to infer genetic interactions from pairwise CRISPR screens

Bioconductor version: Release (3.21)

GEMINI uses log-fold changes to model sample-dependent and independent effects, and uses a variational Bayes approach to infer these effects. The inferred effects are used to score and identify genetic interactions, such as lethality and recovery. More details can be found in Zamanighomi et al. 2019 (in press).

Author: Mahdi Zamanighomi [aut], Sidharth Jain [aut, cre]

Maintainer: Sidharth Jain <sidharthsjain at gmail.com>

Citation (from within R, enter citation("gemini")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("gemini")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("gemini")

Details biocViews Bayesian, CRISPR, DataImport, Software Version 1.22.0 In Bioconductor since BioC 3.10 (R-3.6) (5.5 years) License BSD_3_clause + file LICENSE Depends R (>= 4.1.0) Imports dplyr, grDevices, ggplot2, magrittr, mixtools, scales, pbmcapply, parallel, stats, utils System Requirements URL Bug Reports https://github.com/sellerslab/gemini/issues See More Package Archives

Follow Installation instructions to use this package in your R session.

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