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Bioconductor - cageminer

cageminer

This is the released version of cageminer; for the devel version, see cageminer.

Candidate Gene Miner

Bioconductor version: Release (3.21)

This package aims to integrate GWAS-derived SNPs and coexpression networks to mine candidate genes associated with a particular phenotype. For that, users must define a set of guide genes, which are known genes involved in the studied phenotype. Additionally, the mined candidates can be given a score that favor candidates that are hubs and/or transcription factors. The scores can then be used to rank and select the top n most promising genes for downstream experiments.

Author: Fabrício Almeida-Silva [aut, cre] ORCID: 0000-0002-5314-2964 , Thiago Venancio [aut] ORCID: 0000-0002-2215-8082

Maintainer: Fabrício Almeida-Silva <fabricio_almeidasilva at hotmail.com>

Citation (from within R, enter citation("cageminer")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("cageminer")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("cageminer")
Mining high-confidence candidate genes with cageminer HTML R Script Reference Manual PDF NEWS Text Details biocViews FunctionalGenomics, FunctionalPrediction, GeneExpression, GenomeWideAssociation, Network, NetworkEnrichment, SNP, Software, VariantAnnotation Version 1.14.0 In Bioconductor since BioC 3.14 (R-4.1) (3.5 years) License GPL-3 Depends R (>= 4.1) Imports ggplot2, rlang, ggbio, ggtext, GenomeInfoDb, GenomicRanges, IRanges, reshape2, methods, BioNERO System Requirements URL https://github.com/almeidasilvaf/cageminer Bug Reports https://support.bioconductor.org/t/cageminer See More Package Archives

Follow Installation instructions to use this package in your R session.


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