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Bioconductor - Motif2Site

Motif2Site

This is the released version of Motif2Site; for the devel version, see Motif2Site.

Detect binding sites from motifs and ChIP-seq experiments, and compare binding sites across conditions

Bioconductor version: Release (3.21)

Detect binding sites using motifs IUPAC sequence or bed coordinates and ChIP-seq experiments in bed or bam format. Combine/compare binding sites across experiments, tissues, or conditions. All normalization and differential steps are done using TMM-GLM method. Signal decomposition is done by setting motifs as the centers of the mixture of normal distribution curves.

Author: Peyman Zarrineh [cre, aut] ORCID: 0000-0003-4820-4101

Maintainer: Peyman Zarrineh <peyman.zarrineh at manchester.ac.uk>

Citation (from within R, enter citation("Motif2Site")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Motif2Site")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("Motif2Site")
Details biocViews ChIPSeq, DifferentialPeakCalling, Epigenetics, SequenceMatching, Sequencing, Software Version 1.12.0 In Bioconductor since BioC 3.15 (R-4.2) (3 years) License GPL-2 Depends R (>= 4.1) Imports S4Vectors, stats, utils, methods, grDevices, graphics, BiocGenerics, BSgenome, GenomeInfoDb, MASS, IRanges, GenomicRanges, Biostrings, GenomicAlignments, edgeR, mixtools System Requirements URL Bug Reports https://github.com/fls-bioinformatics-core/Motif2Site/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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