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Bioconductor - MSstatsLOBD

MSstatsLOBD

This is the released version of MSstatsLOBD; for the devel version, see MSstatsLOBD.

Assay characterization: estimation of limit of blanc(LoB) and limit of detection(LOD)

Bioconductor version: Release (3.21)

The MSstatsLOBD package allows calculation and visualization of limit of blac (LOB) and limit of detection (LOD). We define the LOB as the highest apparent concentration of a peptide expected when replicates of a blank sample containing no peptides are measured. The LOD is defined as the measured concentration value for which the probability of falsely claiming the absence of a peptide in the sample is 0.05, given a probability 0.05 of falsely claiming its presence. These functionalities were previously a part of the MSstats package. The methodology is described in Galitzine (2018) .

Author: Devon Kohler [aut, cre], Mateusz Staniak [aut], Cyril Galitzine [aut], Meena Choi [aut], Olga Vitek [aut]

Maintainer: Devon Kohler <kohler.d at northeastern.edu>

Citation (from within R, enter citation("MSstatsLOBD")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MSstatsLOBD")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MSstatsLOBD")
Details biocViews DifferentialExpression, ImmunoOncology, MassSpectrometry, Normalization, OneChannel, Proteomics, QualityControl, Software, TwoChannel Version 1.16.0 In Bioconductor since BioC 3.13 (R-4.1) (4 years) License Artistic-2.0 Depends R (>= 4.0) Imports minpack.lm, ggplot2, utils, stats, grDevices System Requirements URL Bug Reports https://github.com/Vitek-Lab/MSstatsLODQ/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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