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Bioconductor - MIRit

MIRit

This is the released version of MIRit; for the devel version, see MIRit.

Integrate microRNA and gene expression to decipher pathway complexity

Bioconductor version: Release (3.21)

MIRit is an R package that provides several methods for investigating the relationships between miRNAs and genes in different biological conditions. In particular, MIRit allows to explore the functions of dysregulated miRNAs, and makes it possible to identify miRNA-gene regulatory axes that control biological pathways, thus enabling the users to unveil the complexity of miRNA biology. MIRit is an all-in-one framework that aims to help researchers in all the central aspects of an integrative miRNA-mRNA analyses, from differential expression analysis to network characterization.

Author: Jacopo Ronchi [aut, cre] ORCID: 0000-0001-5520-4631 , Maria Foti [fnd] ORCID: 0000-0002-4481-1900

Maintainer: Jacopo Ronchi <jacopo.ronchi at unimib.it>

Citation (from within R, enter citation("MIRit")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MIRit")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MIRit")
Integrate miRNA and gene expression data with MIRit HTML R Script Reference Manual PDF NEWS Text Details biocViews DifferentialExpression, Epigenetics, FunctionalGenomics, GeneExpression, GeneRegulation, Network, NetworkEnrichment, NetworkInference, Pathways, Software, SystemsBiology Version 1.4.1 In Bioconductor since BioC 3.19 (R-4.4) (1 year) License GPL (>= 3) Depends MultiAssayExperiment, R (>= 4.4.0) Imports AnnotationDbi, BiocFileCache, BiocParallel, DESeq2, edgeR, fgsea, genekitr, geneset, ggplot2, ggpubr, graph, graphics, graphite, grDevices, httr, limma, methods, Rcpp, Rgraphviz(>= 2.44.0), rlang, stats, utils System Requirements URL https://github.com/jacopo-ronchi/MIRit Bug Reports https://github.com/jacopo-ronchi/MIRit/issues See More Suggests BiocStyle, biomaRt, BSgenome.Hsapiens.UCSC.hg38, GenomicRanges, ggrepel, ggridges, Gviz, gwasrapidd, knitr, MonoPoly, org.Hs.eg.db, rmarkdown, testthat (>= 3.0.0) Linking To Rcpp Enhances Depends On Me Imports Me Suggests Me Links To Me Build Report Build Report Package Archives

Follow Installation instructions to use this package in your R session.


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