This is the released version of HIPPO; for the devel version, see HIPPO.
Heterogeneity-Induced Pre-Processing tOolBioconductor version: Release (3.21)
For scRNA-seq data, it selects features and clusters the cells simultaneously for single-cell UMI data. It has a novel feature selection method using the zero inflation instead of gene variance, and computationally faster than other existing methods since it only relies on PCA+Kmeans rather than graph-clustering or consensus clustering.
Author: Tae Kim [aut, cre], Mengjie Chen [aut]
Maintainer: Tae Kim <tk382 at uchicago.edu>
Citation (from within R, entercitation("HIPPO")
): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("HIPPO")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("HIPPO")
Details biocViews Clustering, DifferentialExpression, GeneExpression, Sequencing, SingleCell, Software Version 1.20.0 In Bioconductor since BioC 3.11 (R-4.0) (5 years) License GPL (>=2) Depends R (>= 3.6.0) Imports ggplot2, graphics, stats, reshape2, gridExtra, Rtsne, umap, dplyr, rlang, magrittr, irlba, Matrix, SingleCellExperiment, ggrepel System Requirements URL https://github.com/tk382/HIPPO Bug Reports https://github.com/tk382/HIPPO/issues See More Package Archives
Follow Installation instructions to use this package in your R session.
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