This is the released version of G4SNVHunter; for the devel version, see G4SNVHunter.
Evaluating SNV-Induced Disruption of G-Quadruplex StructuresBioconductor version: Release (3.21)
G-quadruplexes (G4s) are unique nucleic acid secondary structures predominantly found in guanine-rich regions and have been shown to be involved in various biological regulatory processes. G4SNVHunter is an R package designed to rapidly identify genomic sequences with G4-forming potential and accurately screen user-provided single nucleotide variants (also applicable to single nucleotide polymorphisms) that may destabilize these structures. This enables users to screen key variants for further experimental study, investigating how these variants may influence biological functions, such as gene regulation, by altering G4 formation.
Author: Rongxin Zhang [cre, aut] ORCID: 0000-0002-1643-1185
Maintainer: Rongxin Zhang <rongxinzhang at outlook.com>
Citation (from within R, entercitation("G4SNVHunter")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("G4SNVHunter")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("G4SNVHunter")Follow Installation instructions to use this package in your R session.
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