This is the released version of CaDrA; for the devel version, see CaDrA.
Candidate Driver AnalysisBioconductor version: Release (3.21)
Performs both stepwise and backward heuristic search for candidate (epi)genetic drivers based on a binary multi-omics dataset. CaDrA's main objective is to identify features which, together, are significantly skewed or enriched pertaining to a given vector of continuous scores (e.g. sample-specific scores representing a phenotypic readout of interest, such as protein expression, pathway activity, etc.), based on the union occurence (i.e. logical OR) of the events.
Author: Reina Chau [aut, cre] ORCID: 0000-0003-3012-1404 , Katia Bulekova [aut] ORCID: 0000-0003-1560-2146 , Vinay Kartha [aut], Stefano Monti [aut] ORCID: 0000-0002-9376-0660
Maintainer: Reina Chau <rchau88 at bu.edu>
Citation (from within R, entercitation("CaDrA")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("CaDrA")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("CaDrA")Follow Installation instructions to use this package in your R session.
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