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Bioconductor - CHETAH

CHETAH

This is the released version of CHETAH; for the devel version, see CHETAH.

Fast and accurate scRNA-seq cell type identification

Bioconductor version: Release (3.21)

CHETAH (CHaracterization of cEll Types Aided by Hierarchical classification) is an accurate, selective and fast scRNA-seq classifier. Classification is guided by a reference dataset, preferentially also a scRNA-seq dataset. By hierarchical clustering of the reference data, CHETAH creates a classification tree that enables a step-wise, top-to-bottom classification. Using a novel stopping rule, CHETAH classifies the input cells to the cell types of the references and to "intermediate types": more general classifications that ended in an intermediate node of the tree.

Author: Jurrian de Kanter [aut, cre], Philip Lijnzaad [aut]

Maintainer: Jurrian de Kanter <jurriandekanter at gmail.com>

Citation (from within R, enter citation("CHETAH")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CHETAH")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CHETAH")
Details biocViews Classification, Clustering, GeneExpression, ImmunoOncology, RNASeq, SingleCell, Software Version 1.24.0 In Bioconductor since BioC 3.9 (R-3.6) (6 years) License file LICENSE Depends R (>= 4.2), ggplot2, SingleCellExperiment Imports shiny, plotly, pheatmap, bioDist, dendextend, cowplot, corrplot, grDevices, stats, graphics, reshape2, S4Vectors, SummarizedExperiment System Requirements URL https://github.com/jdekanter/CHETAH Bug Reports https://github.com/jdekanter/CHETAH See More Package Archives

Follow Installation instructions to use this package in your R session.


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