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Bioconductor - chipseqDB

chipseqDB

This is the released version of chipseqDB; for the devel version, see chipseqDB.

A Bioconductor Workflow to Detect Differential Binding in ChIP-seq Data

Bioconductor version: Release (3.21)

Describes a computational workflow for performing a DB analysis with sliding windows. The aim is to facilitate the practical implementation of window-based DB analyses by providing detailed code and expected output. The workflow described here applies to any ChIP-seq experiment with multiple experimental conditions and multiple biological samples in one or more of the conditions. It detects and summarizes DB regions between conditions in a de novo manner, i.e., without making any prior assumptions about the location or width of bound regions. Detected regions are then annotated according to their proximity to genes.

Author: Aaron Lun [aut, cre], Gordon Smyth [aut]

Maintainer: Aaron Lun <infinite.monkeys.with.keyboards at gmail.com>

Citation (from within R, enter citation("chipseqDB")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("chipseqDB")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("chipseqDB")
1. Introduction HTML 2. Differential enrichment of H3K9ac in B cells HTML 3. Differential binding of CBP in fibroblasts HTML R Script 4. Differential enrichment of H3K27me3 in lung epithelium HTML Details See More Suggests chipseqDBData, BiocStyle, BiocFileCache, ChIPpeakAnno, Gviz, Rsamtools, TxDb.Mmusculus.UCSC.mm10.knownGene, csaw, edgeR, knitr, org.Mm.eg.db, rtracklayer, rmarkdown Linking To Enhances Depends On Me Imports Me Suggests Me Links To Me Package Archives

Follow Installation instructions to use this package in your R session.


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