This is the released version of dorothea; for the devel version, see dorothea.
Collection Of Human And Mouse TF RegulonsBioconductor version: Release (3.21)
DoRothEA is a gene regulatory network containing signed transcription factor (TF) - target gene interactions. DoRothEA regulons, the collection of a TF and its transcriptional targets, were curated and collected from different types of evidence for both human and mouse. A confidence level was assigned to each TF-target interaction based on the number of supporting evidence.
Author: Pau Badia-i-Mompel [cre] ORCID: 0000-0002-1004-3923 , Daniel Dimitrov [aut] ORCID: 0000-0002-5197-2112 , Christian H. Holland [aut] ORCID: 0000-0002-3060-5786 , Luz Garcia-Alonso [aut], Alberto Valdeolivas [ctb], Minoo Ashtiani [ctb], Attila Gabor [ctb]
Maintainer: Pau Badia-i-Mompel <pau.badia at uni-heidelberg.de>
Citation (from within R, entercitation("dorothea")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("dorothea")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("dorothea")Follow Installation instructions to use this package in your R session.
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