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Bioconductor - smoothclust

smoothclust

This is the released version of smoothclust; for the devel version, see smoothclust.

smoothclust

Bioconductor version: Release (3.21)

Method for segmentation of spatial domains and spatially-aware clustering in spatial transcriptomics data. The method generates spatial domains with smooth boundaries by smoothing gene expression profiles across neighboring spatial locations, followed by unsupervised clustering. Spatial domains consisting of consistent mixtures of cell types may then be further investigated by applying cell type compositional analyses or differential analyses.

Author: Lukas M. Weber [aut, cre] ORCID: 0000-0002-3282-1730

Maintainer: Lukas M. Weber <lmweb012 at gmail.com>

Citation (from within R, enter citation("smoothclust")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("smoothclust")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("smoothclust")
Details biocViews Clustering, GeneExpression, SingleCell, Software, Spatial, Transcriptomics Version 1.4.0 In Bioconductor since BioC 3.19 (R-4.4) (1 year) License MIT + file LICENSE Depends R (>= 4.4.0) Imports SpatialExperiment, SummarizedExperiment, sparseMatrixStats, spdep, methods, utils System Requirements URL https://github.com/lmweber/smoothclust Bug Reports https://github.com/lmweber/smoothclust/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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