This is the released version of lute; for the devel version, see lute.
Framework for cell size scale factor normalized bulk transcriptomics deconvolution experimentsBioconductor version: Release (3.21)
Provides a framework for adjustment on cell type size when performing bulk transcripomics deconvolution. The main framework function provides a means of reference normalization using cell size scale factors. It allows for marker selection and deconvolution using non-negative least squares (NNLS) by default. The framework is extensible for other marker selection and deconvolution algorithms, and users may reuse the generics, methods, and classes for these when developing new algorithms.
Author: Sean K Maden [cre, aut] ORCID: 0000-0002-2212-4894 , Stephanie Hicks [aut] ORCID: 0000-0002-7858-0231
Maintainer: Sean K Maden <maden.sean at gmail.com>
Citation (from within R, entercitation("lute")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("lute")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("lute")Follow Installation instructions to use this package in your R session.
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