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Bioconductor - SiPSiC

SiPSiC

This is the released version of SiPSiC; for the devel version, see SiPSiC.

Calculate Pathway Scores for Each Cell in scRNA-Seq Data

Bioconductor version: Release (3.21)

Infer biological pathway activity of cells from single-cell RNA-sequencing data by calculating a pathway score for each cell (pathway genes are specified by the user). It is recommended to have the data in Transcripts-Per-Million (TPM) or Counts-Per-Million (CPM) units for best results. Scores may change when adding cells to or removing cells off the data. SiPSiC stands for Single Pathway analysis in Single Cells.

Author: Daniel Davis [aut, cre] ORCID: 0000-0001-7863-1521 , Yotam Drier [aut]

Maintainer: Daniel Davis <DanielDavis000 at gmail.com>

Citation (from within R, enter citation("SiPSiC")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("SiPSiC")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SiPSiC")
Infer Biological Pathway Activity from Single-Cell RNA-Seq Data HTML R Script Reference Manual PDF NEWS Text LICENSE Text Details biocViews BiomedicalInformatics, CellBiology, DataImport, DifferentialExpression, GeneSetEnrichment, ImmunoOncology, RNASeq, Sequencing, SingleCell, Software, Transcription, Transcriptomics Version 1.8.0 In Bioconductor since BioC 3.17 (R-4.3) (2 years) License file LICENSE Depends Matrix, SingleCellExperiment Imports System Requirements URL https://www.genome.org/cgi/doi/10.1101/gr.278431.123 Bug Reports https://github.com/DanielDavis12/SiPSiC/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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