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Bioconductor - DegCre

DegCre

This is the released version of DegCre; for the devel version, see DegCre.

Probabilistic association of DEGs to CREs from differential data

Bioconductor version: Release (3.21)

DegCre generates associations between differentially expressed genes (DEGs) and cis-regulatory elements (CREs) based on non-parametric concordance between differential data. The user provides GRanges of DEG TSS and CRE regions with differential p-value and optionally log-fold changes and DegCre returns an annotated Hits object with associations and their calculated probabilities. Additionally, the package provides functionality for visualization and conversion to other formats.

Author: Brian S. Roberts [aut, cre] ORCID: 0009-0001-2914-6826

Maintainer: Brian S. Roberts <brianroberts1976 at yahoo.com>

Citation (from within R, enter citation("DegCre")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DegCre")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DegCre")
Details biocViews ATACSeq, ChIPSeq, DNaseSeq, GeneExpression, GeneRegulation, RNASeq, Software Version 1.4.0 In Bioconductor since BioC 3.19 (R-4.4) (1 year) License MIT + file LICENSE Depends R (>= 4.4) Imports GenomicRanges, InteractionSet, plotgardener, S4Vectors, stats, graphics, grDevices, BiocGenerics, GenomeInfoDb, IRanges, BiocParallel, qvalue, TxDb.Hsapiens.UCSC.hg38.knownGene, org.Hs.eg.db, utils System Requirements URL https://github.com/brianSroberts/DegCre Bug Reports https://github.com/brianSroberts/DegCre/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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