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Bioconductor - DSS

DSS

This is the released version of DSS; for the devel version, see DSS.

Dispersion shrinkage for sequencing data

Bioconductor version: Release (3.21)

DSS is an R library performing differntial analysis for count-based sequencing data. It detectes differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a new dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions.

Author: Hao Wu<hao.wu at emory.edu>, Hao Feng<hxf155 at case.edu>

Maintainer: Hao Wu <hao.wu at emory.edu>, Hao Feng <hxf155 at case.edu>

Citation (from within R, enter citation("DSS")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DSS")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DSS")
Details biocViews DNAMethylation, DifferentialExpression, DifferentialMethylation, GeneExpression, RNASeq, Sequencing, Software Version 2.56.0 In Bioconductor since BioC 2.11 (R-2.15) (13 years) License GPL Depends R (>= 3.5.0), methods, Biobase, BiocParallel, bsseq, parallel Imports utils, graphics, stats, splines System Requirements URL See More Package Archives

Follow Installation instructions to use this package in your R session.

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