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Bioconductor - CDI (development version)

CDI

This is the development version of CDI; for the stable release version, see CDI.

Clustering Deviation Index (CDI)

Bioconductor version: Development (3.22)

Single-cell RNA-sequencing (scRNA-seq) is widely used to explore cellular variation. The analysis of scRNA-seq data often starts from clustering cells into subpopulations. This initial step has a high impact on downstream analyses, and hence it is important to be accurate. However, there have not been unsupervised metric designed for scRNA-seq to evaluate clustering performance. Hence, we propose clustering deviation index (CDI), an unsupervised metric based on the modeling of scRNA-seq UMI counts to evaluate clustering of cells.

Author: Jiyuan Fang [cre, aut] ORCID: 0000-0002-5004-4138 , Jichun Xie [ctb], Cliburn Chan [ctb], Kouros Owzar [ctb], Liuyang Wang [ctb], Diyuan Qin [ctb], Qi-Jing Li [ctb], Jichun Xie [ctb]

Maintainer: Jiyuan Fang <jfanglovestats at gmail.com>

Citation (from within R, enter citation("CDI")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("CDI")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CDI")
Details biocViews CellBasedAssays, Clustering, RNASeq, Sequencing, SingleCell, Software, Visualization Version 1.7.0 In Bioconductor since BioC 3.18 (R-4.3) (1.5 years) License GPL-3 + file LICENSE Depends R (>= 3.6) Imports matrixStats, Seurat, SeuratObject, stats, BiocParallel, ggplot2, reshape2, grDevices, ggsci, SingleCellExperiment, SummarizedExperiment, methods System Requirements URL https://github.com/jichunxie/CDI Bug Reports https://github.com/jichunxie/CDI/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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