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Bioconductor - miRspongeR (development version)

miRspongeR

This is the development version of miRspongeR; for the stable release version, see miRspongeR.

Identification and analysis of miRNA sponge regulation

Bioconductor version: Development (3.22)

This package provides several functions to explore miRNA sponge (also called ceRNA or miRNA decoy) regulation from putative miRNA-target interactions or/and transcriptomics data (including bulk, single-cell and spatial gene expression data). It provides eight popular methods for identifying miRNA sponge interactions, and an integrative method to integrate miRNA sponge interactions from different methods, as well as the functions to validate miRNA sponge interactions, and infer miRNA sponge modules, conduct enrichment analysis of miRNA sponge modules, and conduct survival analysis of miRNA sponge modules. By using a sample control variable strategy, it provides a function to infer sample-specific miRNA sponge interactions. In terms of sample-specific miRNA sponge interactions, it implements three similarity methods to construct sample-sample correlation network.

Author: Junpeng Zhang [aut, cre]

Maintainer: Junpeng Zhang <zjp at dali.edu.cn>

Citation (from within R, enter citation("miRspongeR")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("miRspongeR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("miRspongeR")
Identification and analysis of miRNA sponge regulation HTML R Script Reference Manual PDF NEWS Text Details biocViews BiomedicalInformatics, GeneExpression, Microarray, NetworkEnrichment, RNASeq, SingleCell, Software, Spatial, Survival Version 2.13.4 In Bioconductor since BioC 3.9 (R-3.6) (6 years) License GPL-3 Depends R (>= 4.4.0) Imports corpcor, SPONGE, parallel, igraph, MCL, clusterProfiler, ReactomePA, DOSE, survival, grDevices, graphics, stats, utils, Rcpp, RColorBrewer, grid, org.Hs.eg.db, foreach, doParallel System Requirements URL Bug Reports https://github.com/zhangjunpeng411/miRspongeR/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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