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Bioconductor - methyLImp2 (development version)

methyLImp2

This is the development version of methyLImp2; for the stable release version, see methyLImp2.

Missing value estimation of DNA methylation data

Bioconductor version: Development (3.22)

This package allows to estimate missing values in DNA methylation data. methyLImp method is based on linear regression since methylation levels show a high degree of inter-sample correlation. Implementation is parallelised over chromosomes since probes on different chromosomes are usually independent. Mini-batch approach to reduce the runtime in case of large number of samples is available.

Author: Pietro Di Lena [aut] ORCID: 0000-0002-1838-8918 , Anna Plaksienko [aut, cre] ORCID: 0000-0001-9607-057X , Claudia Angelini [aut] ORCID: 0000-0001-8350-8464 , Christine Nardini [aut] ORCID: 0000-0001-7601-321X

Maintainer: Anna Plaksienko <anna at plaxienko.com>

Citation (from within R, enter citation("methyLImp2")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("methyLImp2")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("methyLImp2")
Details biocViews DNAMethylation, MethylationArray, Microarray, Regression, Software Version 1.5.0 In Bioconductor since BioC 3.19 (R-4.4) (1 year) License GPL-3 Depends R (>= 4.3.0), ChAMPdata Imports BiocParallel, parallel, stats, methods, corpcor, SummarizedExperiment, utils System Requirements URL https://github.com/annaplaksienko/methyLImp2 Bug Reports https://github.com/annaplaksienko/methyLImp2/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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