This is the development version of gemini; for the stable release version, see gemini.
GEMINI: Variational inference approach to infer genetic interactions from pairwise CRISPR screensBioconductor version: Development (3.22)
GEMINI uses log-fold changes to model sample-dependent and independent effects, and uses a variational Bayes approach to infer these effects. The inferred effects are used to score and identify genetic interactions, such as lethality and recovery. More details can be found in Zamanighomi et al. 2019 (in press).
Author: Mahdi Zamanighomi [aut], Sidharth Jain [aut, cre]
Maintainer: Sidharth Jain <sidharthsjain at gmail.com>
Citation (from within R, entercitation("gemini")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("gemini")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("gemini")Follow Installation instructions to use this package in your R session.
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