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Bioconductor - MungeSumstats (development version)

MungeSumstats

This is the development version of MungeSumstats; for the stable release version, see MungeSumstats.

Standardise summary statistics from GWAS

Bioconductor version: Development (3.22)

The *MungeSumstats* package is designed to facilitate the standardisation of GWAS summary statistics. It reformats inputted summary statisitics to include SNP, CHR, BP and can look up these values if any are missing. It also pefrorms dozens of QC and filtering steps to ensure high data quality and minimise inter-study differences.

Author: Alan Murphy [aut, cre] ORCID: 0000-0002-2487-8753 , Brian Schilder [aut, ctb] ORCID: 0000-0001-5949-2191 , Nathan Skene [aut] ORCID: 0000-0002-6807-3180

Maintainer: Alan Murphy <alanmurph94 at hotmail.com>

Citation (from within R, enter citation("MungeSumstats")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("MungeSumstats")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MungeSumstats")
Details biocViews ComparativeGenomics, Genetics, GenomeWideAssociation, GenomicVariation, Preprocessing, SNP, Software, WholeGenome Version 1.17.1 In Bioconductor since BioC 3.13 (R-4.1) (4 years) License Artistic-2.0 Depends R (>= 4.1) Imports data.table, utils, R.utils, dplyr, stats, GenomicRanges, GenomeInfoDb, IRanges, ieugwasr (>= 1.0.1), BSgenome, Biostrings, stringr, VariantAnnotation, methods, parallel, rtracklayer(>= 1.59.1), RCurl System Requirements URL https://github.com/neurogenomics/MungeSumstats https://al-murphy.github.io/MungeSumstats/ Bug Reports https://github.com/neurogenomics/MungeSumstats/issues See More Suggests SNPlocs.Hsapiens.dbSNP144.GRCh37, SNPlocs.Hsapiens.dbSNP144.GRCh38, SNPlocs.Hsapiens.dbSNP155.GRCh37, SNPlocs.Hsapiens.dbSNP155.GRCh38, BSgenome.Hsapiens.1000genomes.hs37d5, BSgenome.Hsapiens.NCBI.GRCh38, BiocGenerics, S4Vectors, rmarkdown, markdown, knitr, testthat (>= 3.0.0), UpSetR, BiocStyle, covr, Rsamtools, MatrixGenerics, badger, BiocParallel, GenomicFiles Linking To Enhances Depends On Me Imports Me Suggests Me Links To Me Build Report Build Report Package Archives

Follow Installation instructions to use this package in your R session.


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