This is the development version of DNABarcodeCompatibility; for the stable release version, see DNABarcodeCompatibility.
A Tool for Optimizing Combinations of DNA Barcodes Used in Multiplexed Experiments on Next Generation Sequencing PlatformsBioconductor version: Development (3.22)
The package allows one to obtain optimised combinations of DNA barcodes to be used for multiplex sequencing. In each barcode combination, barcodes are pooled with respect to Illumina chemistry constraints. Combinations can be filtered to keep those that are robust against substitution and insertion/deletion errors thereby facilitating the demultiplexing step. In addition, the package provides an optimiser function to further favor the selection of barcode combinations with least heterogeneity in barcode usage.
Author: Céline Trébeau [cre] ORCID: 0000-0001-6795-5379 , Jacques Boutet de Monvel [aut] ORCID: 0000-0001-6182-3527 , Fabienne Wong Jun Tai [ctb], Raphaël Etournay [aut] ORCID: 0000-0002-2441-9274
Maintainer: Céline Trébeau <ctrebeau at pasteur.fr>
Citation (from within R, entercitation("DNABarcodeCompatibility")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("DNABarcodeCompatibility")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("DNABarcodeCompatibility")Follow Installation instructions to use this package in your R session.
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