This is the development version of ANCOMBC; for the stable release version, see ANCOMBC.
Microbiome differential abudance and correlation analyses with bias correctionBioconductor version: Development (3.22)
ANCOMBC is a package containing differential abundance (DA) and correlation analyses for microbiome data. Specifically, the package includes Analysis of Compositions of Microbiomes with Bias Correction 2 (ANCOM-BC2), Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC), and Analysis of Composition of Microbiomes (ANCOM) for DA analysis, and Sparse Estimation of Correlations among Microbiomes (SECOM) for correlation analysis. Microbiome data are typically subject to two sources of biases: unequal sampling fractions (sample-specific biases) and differential sequencing efficiencies (taxon-specific biases). Methodologies included in the ANCOMBC package are designed to correct these biases and construct statistically consistent estimators.
Author: Huang Lin [cre, aut] ORCID: 0000-0002-4892-7871
Maintainer: Huang Lin <huanglinfrederick at gmail.com>
Citation (from within R, entercitation("ANCOMBC")
): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("ANCOMBC")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("ANCOMBC")
Details biocViews DifferentialExpression, Microbiome, Normalization, Sequencing, Software Version 2.11.1 In Bioconductor since BioC 3.12 (R-4.0) (4.5 years) License Artistic-2.0 Depends R (>= 4.5.0) Imports stats, CVXR, DescTools, Hmisc, MASS, Matrix, Rdpack, doParallel, doRNG, energy, foreach, gtools, lme4, lmerTest, multcomp, nloptr, parallel, utils System Requirements URL https://github.com/FrederickHuangLin/ANCOMBC Bug Reports https://github.com/FrederickHuangLin/ANCOMBC/issues See More Suggests mia(>= 1.6.0), DT, S4Vectors, SingleCellExperiment, SummarizedExperiment, TreeSummarizedExperiment, dplyr, knitr, magrittr, microbiome, phyloseq, rmarkdown, testthat, tidyr, tidyverse Linking To Enhances Depends On Me Imports Me Suggests Me dar, MiscMetabar Links To Me Build Report Build Report Package Archives
Follow Installation instructions to use this package in your R session.
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