This is the development version of trio; for the stable release version, see trio.
Testing of SNPs and SNP Interactions in Case-Parent Trio StudiesBioconductor version: Development (3.22)
Testing SNPs and SNP interactions with a genotypic TDT. This package furthermore contains functions for computing pairwise values of LD measures and for identifying LD blocks, as well as functions for setting up matched case pseudo-control genotype data for case-parent trios in order to run trio logic regression, for imputing missing genotypes in trios, for simulating case-parent trios with disease risk dependent on SNP interaction, and for power and sample size calculation in trio data.
Author: Holger Schwender, Qing Li, Philipp Berger, Christoph Neumann, Margaret Taub, Ingo Ruczinski
Maintainer: Holger Schwender <holger.schw at gmx.de>
Citation (from within R, entercitation("trio")
): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("trio")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("trio")
Trio Logic Regression and genotypic TDT PDF R Script Reference Manual PDF Details biocViews GeneticVariability, Genetics, Microarray, SNP, Software Version 3.47.0 In Bioconductor since BioC 2.13 (R-3.0) (11.5 years) License LGPL-2 Depends R (>= 3.0.1) Imports grDevices, graphics, methods, stats, survival, utils, siggenes, LogicReg (>= 1.6.1), data.table System Requirements URL See More Package Archives
Follow Installation instructions to use this package in your R session.
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