This is the development version of phenomis; for the stable release version, see phenomis.
Postprocessing and univariate analysis of omics dataBioconductor version: Development (3.22)
The 'phenomis' package provides methods to perform post-processing (i.e. quality control and normalization) as well as univariate statistical analysis of single and multi-omics data sets. These methods include quality control metrics, signal drift and batch effect correction, intensity transformation, univariate hypothesis testing, but also clustering (as well as annotation of metabolomics data). The data are handled in the standard Bioconductor formats (i.e. SummarizedExperiment and MultiAssayExperiment for single and multi-omics datasets, respectively; the alternative ExpressionSet and MultiDataSet formats are also supported for convenience). As a result, all methods can be readily chained as workflows. The pipeline can be further enriched by multivariate analysis and feature selection, by using the 'ropls' and 'biosigner' packages, which support the same formats. Data can be conveniently imported from and exported to text files. Although the methods were initially targeted to metabolomics data, most of the methods can be applied to other types of omics data (e.g., transcriptomics, proteomics).
Author: Etienne A. Thevenot [aut, cre] ORCID: 0000-0003-1019-4577 , Natacha Lenuzza [ctb], Marie Tremblay-Franco [ctb], Alyssa Imbert [ctb], Pierrick Roger [ctb], Eric Venot [ctb], Sylvain Dechaumet [ctb]
Maintainer: Etienne A. Thevenot <etienne.thevenot at cea.fr>
Citation (from within R, entercitation("phenomis")
): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("phenomis")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("phenomis")
Details biocViews BatchEffect, Clustering, Coverage, KEGG, MassSpectrometry, Metabolomics, Normalization, Proteomics, QualityControl, Sequencing, Software, StatisticalMethod, Transcriptomics Version 1.11.0 In Bioconductor since BioC 3.16 (R-4.2) (2.5 years) License CeCILL Depends SummarizedExperiment Imports Biobase, biodb, biodbChebi, data.table, futile.logger, ggplot2, ggrepel, graphics, grDevices, grid, htmlwidgets, igraph, limma, methods, MultiAssayExperiment, MultiDataSet, PMCMRplus, plotly, ranger, RColorBrewer, ropls, stats, tibble, tidyr, utils, VennDiagram System Requirements URL https://doi.org/10.1038/s41597-021-01095-3 See More Package Archives
Follow Installation instructions to use this package in your R session.
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