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Bioconductor - methylscaper (development version)

methylscaper

This is the development version of methylscaper; for the stable release version, see methylscaper.

Visualization of Methylation Data

Bioconductor version: Development (3.22)

methylscaper is an R package for processing and visualizing data jointly profiling methylation and chromatin accessibility (MAPit, NOMe-seq, scNMT-seq, nanoNOMe, etc.). The package supports both single-cell and single-molecule data, and a common interface for jointly visualizing both data types through the generation of ordered representational methylation-state matrices. The Shiny app allows for an interactive seriation process of refinement and re-weighting that optimally orders the cells or DNA molecules to discover methylation patterns and nucleosome positioning.

Author: Bacher Rhonda [aut, cre], Parker Knight [aut]

Maintainer: Bacher Rhonda <rbacher at ufl.edu>

Citation (from within R, enter citation("methylscaper")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("methylscaper")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("methylscaper")
Using methylscaper to visualize joint methylation and nucleosome occupancy data HTML R Script Reference Manual PDF NEWS Text Details biocViews DNAMethylation, Epigenetics, NucleosomePositioning, Sequencing, SingleCell, Software, Visualization Version 1.17.0 In Bioconductor since BioC 3.13 (R-4.1) (4 years) License GPL-2 Depends R (>= 4.4.0) Imports shiny, shinyjs, seriation, BiocParallel, seqinr, Biostrings, pwalign, Rfast, grDevices, graphics, stats, utils, tools, methods, shinyFiles, data.table, SummarizedExperiment System Requirements URL https://github.com/rhondabacher/methylscaper/ Bug Reports https://github.com/rhondabacher/methylscaper/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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