This is the development version of decompTumor2Sig; for the stable release version, see decompTumor2Sig.
Decomposition of individual tumors into mutational signatures by signature refittingBioconductor version: Development (3.22)
Uses quadratic programming for signature refitting, i.e., to decompose the mutation catalog from an individual tumor sample into a set of given mutational signatures (either Alexandrov-model signatures or Shiraishi-model signatures), computing weights that reflect the contributions of the signatures to the mutation load of the tumor.
Author: Rosario M. Piro [aut, cre], Sandra Krueger [ctb]
Maintainer: Rosario M. Piro <rmpiro at gmail.com>
Citation (from within R, entercitation("decompTumor2Sig")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("decompTumor2Sig")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("decompTumor2Sig")Follow Installation instructions to use this package in your R session.
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