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Bioconductor - Summix (development version)

Summix

This is the development version of Summix; for the stable release version, see Summix.

Summix2: A suite of methods to estimate, adjust, and leverage substructure in genetic summary data

Bioconductor version: Development (3.22)

This package contains the Summix2 method for estimating and adjusting for substructure in genetic summary allele frequency data. The function summix() estimates reference group proportions using a mixture model. The adjAF() function produces adjusted allele frequencies for an observed group with reference group proportions matching a target individual or sample. The summix_local() function estimates local ancestry mixture proportions and performs selection scans in genetic summary data.

Author: Audrey Hendricks [cre], Price Adelle [aut], Stoneman Haley [aut]

Maintainer: Audrey Hendricks <audrey.hendricks at cuanschutz.edu>

Citation (from within R, enter citation("Summix")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("Summix")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("Summix")
Details biocViews Genetics, Software, StatisticalMethod, WholeGenome Version 2.15.0 In Bioconductor since BioC 3.13 (R-4.1) (4 years) License MIT + file LICENSE Depends R (>= 4.3) Imports dplyr, nloptr, magrittr, methods, tibble, tidyselect, BEDASSLE, scales, visNetwork, randomcoloR System Requirements URL Bug Reports https://github.com/Bioconductor/Summix/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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