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Bioconductor - EpiDISH (development version)

EpiDISH

This is the development version of EpiDISH; for the stable release version, see EpiDISH.

Epigenetic Dissection of Intra-Sample-Heterogeneity

Bioconductor version: Development (3.22)

EpiDISH is a R package to infer the proportions of a priori known cell-types present in a sample representing a mixture of such cell-types. Right now, the package can be used on DNAm data of blood-tissue of any age, from birth to old-age, generic epithelial tissue and breast tissue. Besides, the package provides a function that allows the identification of differentially methylated cell-types and their directionality of change in Epigenome-Wide Association Studies.

Author: Andrew E. Teschendorff [aut], Shijie C. Zheng [aut, cre]

Maintainer: Shijie C. Zheng <shijieczheng at gmail.com>

Citation (from within R, enter citation("EpiDISH")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("EpiDISH")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("EpiDISH")
Epigenetic Dissection of Intra-Sample-Heterogeneity HTML R Script Reference Manual PDF NEWS Text Details biocViews DNAMethylation, DifferentialMethylation, Epigenetics, ImmunoOncology, MethylationArray, Software Version 2.25.0 In Bioconductor since BioC 3.6 (R-3.4) (7.5 years) License GPL-2 Depends R (>= 4.1) Imports MASS, e1071, quadprog, parallel, stats, matrixStats, stringr, locfdr, Matrix System Requirements URL https://github.com/sjczheng/EpiDISH Bug Reports https://github.com/sjczheng/EpiDISH/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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