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Bioconductor - ELViS (development version)

ELViS

This is the development version of ELViS; for the stable release version, see ELViS.

An R Package for Estimating Copy Number Levels of Viral Genome Segments Using Base-Resolution Read Depth Profile

Bioconductor version: Development (3.22)

Base-resolution copy number analysis of viral genome. Utilizes base-resolution read depth data over viral genome to find copy number segments with two-dimensional segmentation approach. Provides publish-ready figures, including histograms of read depths, coverage line plots over viral genome annotated with copy number change events and viral genes, and heatmaps showing multiple types of data with integrative clustering of samples.

Author: Hyo Young Choi [aut, cph] ORCID: 0000-0002-7627-8493 , Jin-Young Lee [aut, cre, cph] ORCID: 0000-0002-5366-7488 , Xiaobei Zhao [ctb] ORCID: 0000-0002-5277-0846 , Jeremiah R. Holt [ctb] ORCID: 0000-0002-5201-5015 , Katherine A. Hoadley [aut] ORCID: 0000-0002-1216-477X , D. Neil Hayes [aut, fnd, cph] ORCID: 0000-0001-6203-7771

Maintainer: Jin-Young Lee <jlee307 at uthsc.edu>

Citation (from within R, enter citation("ELViS")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("ELViS")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("ELViS")
Details biocViews BiomedicalInformatics, Clustering, CopyNumberVariation, Coverage, GenomicVariation, Normalization, Sequencing, Software, Visualization Version 1.1.0 In Bioconductor since BioC 3.21 (R-4.5) (< 6 months) License MIT + file LICENSE Depends R (>= 4.5.0) Imports basilisk, BiocGenerics, circlize, ComplexHeatmap, data.table, dplyr, GenomicFeatures, GenomicRanges, ggplot2, glue, graphics, grDevices, igraph, IRanges, magrittr, memoise, methods, parallel, patchwork, scales, segclust2d, stats, stringr, txdbmaker, utils, uuid, zoo System Requirements URL https://github.com/hyochoi/ELViS Bug Reports https://github.com/hyochoi/ELViS/issues See More Package Archives

Follow Installation instructions to use this package in your R session.


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