This is the development version of spillR; for the stable release version, see spillR.
Spillover Compensation in Mass Cytometry DataBioconductor version: Development (3.22)
Channel interference in mass cytometry can cause spillover and may result in miscounting of protein markers. We develop a nonparametric finite mixture model and use the mixture components to estimate the probability of spillover. We implement our method using expectation-maximization to fit the mixture model.
Author: Marco Guazzini [aut, cre] ORCID: 0009-0007-8111-5772 , Alexander G. Reisach [aut] ORCID: 0009-0003-5057-6278 , Sebastian Weichwald [aut] ORCID: 0000-0003-0169-7244 , Christof Seiler [aut] ORCID: 0000-0001-8802-3642
Maintainer: Marco Guazzini <m.guazzini at student.maastrichtuniversity.nl>
Citation (from within R, entercitation("spillR")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("spillR")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("spillR")Follow Installation instructions to use this package in your R session.
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