This is the development version of RVS; for the stable release version, see RVS.
Computes estimates of the probability of related individuals sharing a rare variantBioconductor version: Development (3.22)
Rare Variant Sharing (RVS) implements tests of association and linkage between rare genetic variant genotypes and a dichotomous phenotype, e.g. a disease status, in family samples. The tests are based on probabilities of rare variant sharing by relatives under the null hypothesis of absence of linkage and association between the rare variants and the phenotype and apply to single variants or multiple variants in a region (e.g. gene-based test).
Author: Alexandre Bureau, Ingo Ruczinski, Samuel Younkin, Thomas Sherman
Maintainer: Alexandre Bureau <alexandre.bureau at fmed.ulaval.ca>
Citation (from within R, entercitation("RVS")): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("RVS")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("RVS")Follow Installation instructions to use this package in your R session.
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