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Showing content from https://www.bioconductor.org/packages/devel/bioc/html/../../bioc/html/PPInfer.html below:

Bioconductor - PPInfer (development version)

PPInfer

This is the development version of PPInfer; for the stable release version, see PPInfer.

Inferring functionally related proteins using protein interaction networks

Bioconductor version: Development (3.22)

Interactions between proteins occur in many, if not most, biological processes. Most proteins perform their functions in networks associated with other proteins and other biomolecules. This fact has motivated the development of a variety of experimental methods for the identification of protein interactions. This variety has in turn ushered in the development of numerous different computational approaches for modeling and predicting protein interactions. Sometimes an experiment is aimed at identifying proteins closely related to some interesting proteins. A network based statistical learning method is used to infer the putative functions of proteins from the known functions of its neighboring proteins on a PPI network. This package identifies such proteins often involved in the same or similar biological functions.

Author: Dongmin Jung, Xijin Ge

Maintainer: Dongmin Jung <dmdmjung at gmail.com>

Citation (from within R, enter citation("PPInfer")): Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("PPInfer")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("PPInfer")
Details biocViews GeneSetEnrichment, GraphAndNetwork, Network, NetworkEnrichment, Pathways, Software, StatisticalMethod Version 1.35.0 In Bioconductor since BioC 3.5 (R-3.4) (8 years) License Artistic-2.0 Depends biomaRt, fgsea, kernlab, ggplot2, igraph, STRINGdb, yeastExpData Imports httr, grDevices, graphics, stats, utils System Requirements URL See More Suggests Linking To Enhances Depends On Me gsean Imports Me Suggests Me Links To Me Build Report Build Report Package Archives

Follow Installation instructions to use this package in your R session.


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