This is the development version of airpart; for the stable release version, see airpart.
Differential cell-type-specific allelic imbalanceBioconductor version: Development (3.22)
Airpart identifies sets of genes displaying differential cell-type-specific allelic imbalance across cell types or states, utilizing single-cell allelic counts. It makes use of a generalized fused lasso with binomial observations of allelic counts to partition cell types by their allelic imbalance. Alternatively, a nonparametric method for partitioning cell types is offered. The package includes a number of visualizations and quality control functions for examining single cell allelic imbalance datasets.
Author: Wancen Mu [aut, cre] ORCID: 0000-0002-5061-7581 , Michael Love [aut, ctb] ORCID: 0000-0001-8401-0545
Maintainer: Wancen Mu <wancen at live.unc.edu>
Citation (from within R, entercitation("airpart")
): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("airpart")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("airpart")
Details biocViews ATACSeq, CellBiology, ChIPSeq, Clustering, DifferentialExpression, FunctionalGenomics, GeneExpression, GeneRegulation, GraphAndNetwork, QualityControl, RNASeq, Regression, Sequencing, SingleCell, Software, Transcription, TranscriptomeVariant Version 1.17.0 In Bioconductor since BioC 3.13 (R-4.1) (4 years) License GPL-2 Depends R (>= 4.1) Imports SingleCellExperiment, SummarizedExperiment, S4Vectors, scater, stats, smurf, apeglm(>= 1.13.3), emdbook, mclust, clue, dynamicTreeCut, matrixStats, dplyr, plyr, ggplot2, ComplexHeatmap, forestplot, RColorBrewer, rlang, lpSolve, grid, grDevices, graphics, utils, pbapply System Requirements URL https://github.com/Wancen/airpart Bug Reports https://github.com/Wancen/airpart/issues See More Package Archives
Follow Installation instructions to use this package in your R session.
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