This is the development version of CTSV; for the stable release version, see CTSV.
Identification of cell-type-specific spatially variable genes accounting for excess zerosBioconductor version: Development (3.22)
The R package CTSV implements the CTSV approach developed by Jinge Yu and Xiangyu Luo that detects cell-type-specific spatially variable genes accounting for excess zeros. CTSV directly models sparse raw count data through a zero-inflated negative binomial regression model, incorporates cell-type proportions, and performs hypothesis testing based on R package pscl. The package outputs p-values and q-values for genes in each cell type, and CTSV is scalable to datasets with tens of thousands of genes measured on hundreds of spots. CTSV can be installed in Windows, Linux, and Mac OS.
Author: Jinge Yu Developer [aut, cre], Xiangyu Luo Developer [aut]
Maintainer: Jinge Yu Developer <yjgruc at ruc.edu.cn>
Citation (from within R, entercitation("CTSV")
): Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("CTSV")
For older versions of R, please refer to the appropriate Bioconductor release.
DocumentationTo view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("CTSV")
Details biocViews GeneExpression, Genetics, Regression, Software, Spatial, StatisticalMethod Version 1.11.0 In Bioconductor since BioC 3.16 (R-4.2) (2.5 years) License GPL-3 Depends R (>= 4.2) Imports stats, pscl, qvalue, BiocParallel, methods, knitr, SpatialExperiment, SummarizedExperiment System Requirements URL https://github.com/jingeyu/CTSV Bug Reports https://github.com/jingeyu/CTSV/issues See More Package Archives
Follow Installation instructions to use this package in your R session.
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