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Testing two-tailed p-values using Stouffer's approach

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About combining multiple test statistics, Wikipedia says

This Z-score (for the overall meta-analysis) is appropriate for one-sided right-tailed p-values; minor modifications can be made if two-sided or left-tailed p-values are being analyzed.

What are those minor modifications?

krlmlr

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asked Dec 21, 2011 at 19:09

Joel W.Joel W.

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1) If two-sided p-values are being analyzed, you use the two-sided p-value in the calculation of the $Z_i$. The two-sided p-value is $\tilde{p}_i = p_i/2$.

2) If left-tailed p-values are used, you use $1-p_i$ instead of $p_i$ in the calculation of the $Z_i$.

answered Dec 21, 2011 at 19:32

jbowmanjbowman

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