pysam — a Python package for reading, manipulating, and writing genomic data sets.
pysam is a lightweight wrapper of the HTSlib API and provides facilities to read and write SAM/BAM/CRAM/VCF/BCF/BED/GFF/GTF/FASTA/FASTQ files as well as access to the command-line functionality of samtools and bcftools. The module supports compression and random access through indexing.
This module provides a low-level wrapper around HTSlib’s C API using Cython and a high-level API for convenient access to the data within standard genomic file formats.
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