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Comorbidity measures for use with administrative dataA Elixhauser et al. Med Care. 1998 Jan.
doi: 10.1097/00005650-199801000-00004. AffiliationItem in Clipboard
AbstractObjectives: This study attempts to develop a comprehensive set of comorbidity measures for use with large administrative inpatient datasets.
Methods: The study involved clinical and empirical review of comorbidity measures, development of a framework that attempts to segregate comorbidities from other aspects of the patient's condition, development of a comorbidity algorithm, and testing on heterogeneous and homogeneous patient groups. Data were drawn from all adult, nonmaternal inpatients from 438 acute care hospitals in California in 1992 (n = 1,779,167). Outcome measures were those commonly available in administrative data: length of stay, hospital charges, and in-hospital death.
Results: A comprehensive set of 30 comorbidity measures was developed. The comorbidities were associated with substantial increases in length of stay, hospital charges, and mortality both for heterogeneous and homogeneous disease groups. Several comorbidities are described that are important predictors of outcomes, yet commonly are not measured. These include mental disorders, drug and alcohol abuse, obesity, coagulopathy, weight loss, and fluid and electrolyte disorders.
Conclusions: The comorbidities had independent effects on outcomes and probably should not be simplified as an index because they affect outcomes differently among different patient groups. The present method addresses some of the limitations of previous measures. It is based on a comprehensive approach to identifying comorbidities and separates them from the primary reason for hospitalization, resulting in an expanded set of comorbidities that easily is applied without further refinement to administrative data for a wide range of diseases.
Comment inBlack C, Roos NP. Black C, et al. Med Care. 1998 Jan;36(1):3-5. doi: 10.1097/00005650-199801000-00002. Med Care. 1998. PMID: 9431326 Review. No abstract available.
Sharma M, Sonig A, Ambekar S, Nanda A. Sharma M, et al. J Neurosurg Spine. 2014 Feb;20(2):125-41. doi: 10.3171/2013.9.SPINE13274. Epub 2013 Nov 29. J Neurosurg Spine. 2014. PMID: 24286530
Kaul P, Federspiel JJ, Dai X, Stearns SC, Smith SC Jr, Yeung M, Beyhaghi H, Zhou L, Stouffer GA. Kaul P, et al. JAMA. 2014 Nov 19;312(19):1999-2007. doi: 10.1001/jama.2014.15236. JAMA. 2014. PMID: 25399275 Free PMC article.
Amato L, Colais P, Davoli M, Ferroni E, Fusco D, Minozzi S, Moirano F, Sciattella P, Vecchi S, Ventura M, Perucci CA. Amato L, et al. Epidemiol Prev. 2013 Mar-Jun;37(2-3 Suppl 2):1-100. Epidemiol Prev. 2013. PMID: 23851286 Review. Italian.
Yurkovich M, Avina-Zubieta JA, Thomas J, Gorenchtein M, Lacaille D. Yurkovich M, et al. J Clin Epidemiol. 2015 Jan;68(1):3-14. doi: 10.1016/j.jclinepi.2014.09.010. Epub 2014 Oct 31. J Clin Epidemiol. 2015. PMID: 25441702 Review.
Chen LM, Birkmeyer JD, Saint S, Jha AK. Chen LM, et al. J Hosp Med. 2013 Mar;8(3):126-31. doi: 10.1002/jhm.2001. Epub 2013 Jan 3. J Hosp Med. 2013. PMID: 23288691 Free PMC article.
Ragulin-Coyne E, Witkowski ER, Chau Z, Ng SC, Santry HP, Callery MP, Shah SA, Tseng JF. Ragulin-Coyne E, et al. J Gastrointest Surg. 2013 Mar;17(3):434-42. doi: 10.1007/s11605-012-2119-8. Epub 2013 Jan 5. J Gastrointest Surg. 2013. PMID: 23292460 Free PMC article.
Kim JW, Chun EJ, Choi SI, Park DJ, Kim HH, Bang SM, Kim MJ, Lee JH, Lee MS, Lee JO, Kim YJ, Kim JH, Lee JS, Lee KW. Kim JW, et al. PLoS One. 2013 Apr 17;8(4):e61968. doi: 10.1371/journal.pone.0061968. Print 2013. PLoS One. 2013. PMID: 23613988 Free PMC article.
Eskander MF, Bliss LA, Yousafzai OK, de Geus SW, Ng SC, Callery MP, Kent TS, Moser AJ, Khwaja K, Tseng JF. Eskander MF, et al. HPB (Oxford). 2015 Sep;17(9):753-62. doi: 10.1111/hpb.12436. Epub 2015 Jun 20. HPB (Oxford). 2015. PMID: 26096061 Free PMC article.
Elkafrawy AA, Ahmed M, Alomari M, Elkaryoni A, Kennedy KF, Clarkston WK, Campbell DR. Elkafrawy AA, et al. World J Clin Cases. 2021 Feb 16;9(5):1048-1057. doi: 10.12998/wjcc.v9.i5.1048. World J Clin Cases. 2021. PMID: 33644168 Free PMC article.
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