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The PRISMA 2020 statement: An updated guideline for reporting systematic reviews

doi: 10.1016/j.jclinepi.2021.03.001. Epub 2021 Mar 29. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews Matthew J Page¹, Joanne E McKenzie², Patrick M Bossuyt³, Isabelle Boutron⁴, Tammy C Hoffmann⁵, Cynthia D Mulrow⁶, Larissa Shamseer⁷, Jennifer M Tetzlaff⁸, Elie A Akl⁹, Sue E Brennan², Roger Chou¹⁰, Julie Glanville¹¹, Jeremy M Grimshaw¹², Asbjørn Hróbjartsson¹³, Manoj M Lalu¹⁴, Tianjing Li¹⁵, Elizabeth W Loder¹⁶, Evan Mayo-Wilson¹⁷, Steve McDonald², Luke A McGuinness¹⁸, Lesley A Stewart¹⁹, James Thomas²⁰, Andrea C Tricco²¹, Vivian A Welch²², Penny Whiting¹⁸, David Moher²³

Affiliations

¹ School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia. Electronic address: matthew.page@monash.edu.
² School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
³ Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.
⁴ Université de Paris, Centre of Epidemiology and Statistics (CRESS), Inserm, F 75004, Paris, France.
⁵ Institute for Evidence-Based Healthcare, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Australia.
⁶ University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
⁷ Knowledge Translation Program, Li Ka Shing Knowledge Institute, Toronto, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
⁸ Evidence Partners, Ottawa, Canada.
⁹ Clinical Research Institute, American University of Beirut, Beirut, Lebanon; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
¹⁰ Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR, USA.
¹¹ York Health Economics Consortium (YHEC Ltd), University of York, York, UK.
¹² Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada; Department of Medicine, University of Ottawa, Ottawa, Canada.
¹³ Centre for Evidence-Based Medicine Odense (CEBMO) and Cochrane Denmark, Department of Clinical Research, University of Southern Denmark, JB Winsløwsvej 9b, 3(rd) Floor, 5000 Odense, Denmark; Open Patient data Exploratory Network (OPEN), Odense University Hospital, Odense, Denmark.
¹⁴ Department of Anesthesiology and Pain Medicine, The Ottawa Hospital, Ottawa, Canada; Clinical Epidemiology Program, Blueprint Translational Research Group, Ottawa Hospital Research Institute, Ottawa, Canada; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada.
¹⁵ Department of Ophthalmology, School of Medicine, University of Colorado Denver, Denver, Colorado, United State; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
¹⁶ Division of Headache, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Head of Research, The BMJ, London, UK.
¹⁷ Department of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, IN, USA.
¹⁸ Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
¹⁹ Centre for Reviews and Dissemination, University of York, York, UK.
²⁰ EPPI-Centre, UCL Social Research Institute, University College London, London, UK.
²¹ Li Ka Shing Knowledge Institute of St. Michael's Hospital, Unity Health Toronto, Toronto, Canada; Epidemiology Division of the Dalla Lana School of Public Health and the Institute of Health Management, Policy, and Evaluation, University of Toronto, Toronto, Canada; Queen's Collaboration for Health Care Quality Joanna Briggs Institute Centre of Excellence, Queen's University, Kingston, Canada.
²² Methods Centre, Bruyère Research Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
²³ Centre for Journalology, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.

PMID: 33789819
DOI: 10.1016/j.jclinepi.2021.03.001

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The PRISMA 2020 statement: An updated guideline for reporting systematic reviews

Matthew J Page et al. J Clin Epidemiol. 2021 Jun.

Free article doi: 10.1016/j.jclinepi.2021.03.001. Epub 2021 Mar 29. Authors Matthew J Page¹, Joanne E McKenzie², Patrick M Bossuyt³, Isabelle Boutron⁴, Tammy C Hoffmann⁵, Cynthia D Mulrow⁶, Larissa Shamseer⁷, Jennifer M Tetzlaff⁸, Elie A Akl⁹, Sue E Brennan², Roger Chou¹⁰, Julie Glanville¹¹, Jeremy M Grimshaw¹², Asbjørn Hróbjartsson¹³, Manoj M Lalu¹⁴, Tianjing Li¹⁵, Elizabeth W Loder¹⁶, Evan Mayo-Wilson¹⁷, Steve McDonald², Luke A McGuinness¹⁸, Lesley A Stewart¹⁹, James Thomas²⁰, Andrea C Tricco²¹, Vivian A Welch²², Penny Whiting¹⁸, David Moher²³ Affiliations

¹ School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia. Electronic address: matthew.page@monash.edu.
² School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
³ Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.
⁴ Université de Paris, Centre of Epidemiology and Statistics (CRESS), Inserm, F 75004, Paris, France.
⁵ Institute for Evidence-Based Healthcare, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Australia.
⁶ University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
⁷ Knowledge Translation Program, Li Ka Shing Knowledge Institute, Toronto, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
⁸ Evidence Partners, Ottawa, Canada.
⁹ Clinical Research Institute, American University of Beirut, Beirut, Lebanon; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
¹⁰ Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR, USA.
¹¹ York Health Economics Consortium (YHEC Ltd), University of York, York, UK.
¹² Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada; Department of Medicine, University of Ottawa, Ottawa, Canada.
¹³ Centre for Evidence-Based Medicine Odense (CEBMO) and Cochrane Denmark, Department of Clinical Research, University of Southern Denmark, JB Winsløwsvej 9b, 3(rd) Floor, 5000 Odense, Denmark; Open Patient data Exploratory Network (OPEN), Odense University Hospital, Odense, Denmark.
¹⁴ Department of Anesthesiology and Pain Medicine, The Ottawa Hospital, Ottawa, Canada; Clinical Epidemiology Program, Blueprint Translational Research Group, Ottawa Hospital Research Institute, Ottawa, Canada; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada.
¹⁵ Department of Ophthalmology, School of Medicine, University of Colorado Denver, Denver, Colorado, United State; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
¹⁶ Division of Headache, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Head of Research, The BMJ, London, UK.
¹⁷ Department of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, IN, USA.
¹⁸ Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
¹⁹ Centre for Reviews and Dissemination, University of York, York, UK.
²⁰ EPPI-Centre, UCL Social Research Institute, University College London, London, UK.
²¹ Li Ka Shing Knowledge Institute of St. Michael's Hospital, Unity Health Toronto, Toronto, Canada; Epidemiology Division of the Dalla Lana School of Public Health and the Institute of Health Management, Policy, and Evaluation, University of Toronto, Toronto, Canada; Queen's Collaboration for Health Care Quality Joanna Briggs Institute Centre of Excellence, Queen's University, Kingston, Canada.
²² Methods Centre, Bruyère Research Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
²³ Centre for Journalology, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.

PMID: 33789819
DOI: 10.1016/j.jclinepi.2021.03.001

Item in Clipboard

Abstract

The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. Over the past decade, advances in systematic review methodology and terminology have necessitated an update to the guideline. The PRISMA 2020 statement replaces the 2009 statement and includes new reporting guidance that reflects advances in methods to identify, select, appraise, and synthesise studies. The structure and presentation of the items have been modified to facilitate implementation. In this article, we present the PRISMA 2020 27-item checklist, an expanded checklist that details reporting recommendations for each item, the PRISMA 2020 abstract checklist, and the revised flow diagrams for original and updated reviews.

Keywords: Checklist; Meta-analysis; Reporting guideline; Reproducibility; Systematic review; Transparency.

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