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Showing content from https://pubmed.ncbi.nlm.nih.gov/33213391/ below:

COVID-19 mortality risk for older men and women

. 2020 Nov 19;20(1):1742. doi: 10.1186/s12889-020-09826-8. COVID-19 mortality risk for older men and women

Affiliations

¹ Department of Anesthesiology, 333 Cedar Street, TMP-3, New Haven, CT, 06510, USA. david.yanez@yale.edu.
² Department of Epidemiology, University of Washington, Seattle, Washington, USA.
³ State Department of Health, Geneva, Switzerland.
⁴ Department of Anesthesiology, 333 Cedar Street, TMP-3, New Haven, CT, 06510, USA.

PMID: 33213391
PMCID: PMC7675386
DOI: 10.1186/s12889-020-09826-8

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COVID-19 mortality risk for older men and women

N David Yanez et al. BMC Public Health. 2020.

. 2020 Nov 19;20(1):1742. doi: 10.1186/s12889-020-09826-8. Affiliations

¹ Department of Anesthesiology, 333 Cedar Street, TMP-3, New Haven, CT, 06510, USA. david.yanez@yale.edu.
² Department of Epidemiology, University of Washington, Seattle, Washington, USA.
³ State Department of Health, Geneva, Switzerland.
⁴ Department of Anesthesiology, 333 Cedar Street, TMP-3, New Haven, CT, 06510, USA.

PMID: 33213391
PMCID: PMC7675386
DOI: 10.1186/s12889-020-09826-8

Item in Clipboard

Abstract

Background: Case-fatality from COVID-19 has been reported to be relatively high in patients age 65 years or older. We sought to determine the age-specific rates of COVID-19 mortality at the population level.

Methods: We obtained information regarding the total number of COVID-19 reported deaths for six consecutive weeks beginning at the 50th recorded death, among 16 countries that reported a relatively high number of COVID-19 cases as of April 12, 2020. We performed an ecological study to model COVID-19 mortality rates per week by age group (54 years or younger, 55-64 years, and 65 years or older) and sex using a Poisson mixed effects regression model.

Results: Over the six-week period of data, there were 178,568 COVID-19 deaths from a total population of approximately 2.4 billion people. Age and sex were associated with COVID-19 mortality. Compared with individuals ages 54 years or younger, the incident rate ratio (IRR) was 8.1, indicating that the mortality rate of COVID-19 was 8.1 times higher (95%CI = 7.7, 8.5) among those 55 to 64 years, and more than 62 times higher (IRR = 62.1; 95%CI = 59.7, 64.7) among those ages 65 or older. Mortality rates from COVID-19 were 77% higher in men than in women (IRR = 1.77, 95%CI = 1.74, 1.79).

Conclusions: In the 16 countries examined, persons age 65 years or older had strikingly higher COVID-19 mortality rates compared to younger individuals, and men had a higher risk of COVID-19 death than women.

Keywords: Age; Pandemic; Population health; Severe acute respiratory syndrome-CoronaVirus-2, epidemiology.

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Conflict of interest statement

The authors declare they have no competing interests.

Figures
Fig. 1

COVID-19 actual and estimated average…

Fig. 1

COVID-19 actual and estimated average number of weekly deaths for six consecutive weeks…

Fig. 1

COVID-19 actual and estimated average number of weekly deaths for six consecutive weeks beginning with the 50th recorded death, among 16 countries that reported a relatively high number of COVID-19 cases as of April 12, 2020. Part A women, Part B men

Fig. 2

COVID-19 actual and estimated weekly…

Fig. 2

COVID-19 actual and estimated weekly death rates for six consecutive weeks beginning with…

Fig. 2

COVID-19 actual and estimated weekly death rates for six consecutive weeks beginning with the 50th recorded death, among 16 countries that reported a relatively high number of COVID-19 cases as of April 12, 2020. Part A women, Part B men