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Showing content from https://pubmed.ncbi.nlm.nih.gov/32758438/ below:

Risk of COVID-19 in health-care workers in Denmark: an observational cohort study

Observational Study

Affiliations

• ¹ Department of Cardiology, Herlev og Gentofte Hospital, University of Copenhagen, Herlev, Denmark; Department of Emergency Medicine, Herlev og Gentofte Hospital, University of Copenhagen, Herlev, Denmark. Electronic address: kasper.karmark.iversen@regionh.dk.
• ² Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
• ³ Department of Cardiology, Herlev og Gentofte Hospital, University of Copenhagen, Herlev, Denmark; Department of Emergency Medicine, Herlev og Gentofte Hospital, University of Copenhagen, Herlev, Denmark.
• ⁴ Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Infectious Disease, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
• ⁵ Department of Neurology, Rigshospitalet Glostrup, University of Copenhagen, Glostrup, Denmark.
• ⁶ Department of Emergency and Clinical Research Centre, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
• ⁷ Department of Clinical Research, Nordsjællands Hospital, Hillerød, Denmark.
• ⁸ Department of Clinical Biochemistry, Nordsjællands Hospital, Hillerød, Denmark.
• ⁹ Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.
• ¹⁰ Department of Endocrinology and Copenhagen Center for Translational Research, Bispebjerg Hospital, Copenhagen, Denmark.
• ¹¹ Department of Pulmonary Medicine and Copenhagen Center for Translational Research, Bispebjerg Hospital, Copenhagen, Denmark.
• ¹² Mental Health Services-The Capital Region of Denmark, Copenhagen, Denmark.
• ¹³ Emergency Medical Services, Ballerup, Copenhagen, Denmark.
• ¹⁴ Diagnostisk Enhed, Bornholms Hospital, Rønne, Denmark.
• ¹⁵ Department of Infectious Disease, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
• ¹⁶ Department of Infectious Disease, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

• PMID: 32758438
• PMCID: PMC7398038
• DOI: 10.1016/S1473-3099(20)30589-2

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Observational Study

Kasper Iversen et al. Lancet Infect Dis. 2020 Dec.

• ¹ Department of Cardiology, Herlev og Gentofte Hospital, University of Copenhagen, Herlev, Denmark; Department of Emergency Medicine, Herlev og Gentofte Hospital, University of Copenhagen, Herlev, Denmark. Electronic address: kasper.karmark.iversen@regionh.dk.
• ² Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
• ³ Department of Cardiology, Herlev og Gentofte Hospital, University of Copenhagen, Herlev, Denmark; Department of Emergency Medicine, Herlev og Gentofte Hospital, University of Copenhagen, Herlev, Denmark.
• ⁴ Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Infectious Disease, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
• ⁵ Department of Neurology, Rigshospitalet Glostrup, University of Copenhagen, Glostrup, Denmark.
• ⁶ Department of Emergency and Clinical Research Centre, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
• ⁷ Department of Clinical Research, Nordsjællands Hospital, Hillerød, Denmark.
• ⁸ Department of Clinical Biochemistry, Nordsjællands Hospital, Hillerød, Denmark.
• ⁹ Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.
• ¹⁰ Department of Endocrinology and Copenhagen Center for Translational Research, Bispebjerg Hospital, Copenhagen, Denmark.
• ¹¹ Department of Pulmonary Medicine and Copenhagen Center for Translational Research, Bispebjerg Hospital, Copenhagen, Denmark.
• ¹² Mental Health Services-The Capital Region of Denmark, Copenhagen, Denmark.
• ¹³ Emergency Medical Services, Ballerup, Copenhagen, Denmark.
• ¹⁴ Diagnostisk Enhed, Bornholms Hospital, Rønne, Denmark.
• ¹⁵ Department of Infectious Disease, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
• ¹⁶ Department of Infectious Disease, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

• PMID: 32758438
• PMCID: PMC7398038
• DOI: 10.1016/S1473-3099(20)30589-2

Item in Clipboard

• Correction to Lancet Infect Dis 2020; published online Aug 3. https://doi.org/10.1016/S1473-3099(20)30589-2.

  [No authors listed] [No authors listed] Lancet Infect Dis. 2020 Oct;20(10):e250. doi: 10.1016/S1473-3099(20)30652-6. Epub 2020 Aug 14. Lancet Infect Dis. 2020. PMID: 32805199 Free PMC article. No abstract available.

Background: Health-care workers are thought to be highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We aimed to investigate the prevalence of antibodies against SARS-CoV-2 in health-care workers and the proportion of seroconverted health-care workers with previous symptoms of COVID-19.

Methods: In this observational cohort study, screening was offered to health-care workers in the Capital Region of Denmark, including medical, nursing, and other students who were associated with hospitals in the region. Screening included point-of-care tests for IgM and IgG antibodies against SARS-CoV-2. Test results and participant characteristics were recorded. Results were compared with findings in blood donors in the Capital Region in the study period.

Findings: Between April 15 and April 23, 2020, we screened 29 295 health-care workers, of whom 28 792 (98·28%) provided their test results. We identified 1163 (4·04% [95% CI 3·82-4·27]) seropositive health-care workers. Seroprevalence was higher in health-care workers than in blood donors (142 [3·04%] of 4672; risk ratio [RR] 1·33 [95% CI 1·12-1·58]; p<0·001). Seroprevalence was higher in male health-care workers (331 [5·45%] of 6077) than in female health-care workers (832 [3·66%] of 22 715; RR 1·49 [1·31-1·68]; p<0·001). Frontline health-care workers working in hospitals had a significantly higher seroprevalence (779 [4·55%] of 16 356) than health-care workers in other settings (384 [3·29%] of 11 657; RR 1·38 [1·22-1·56]; p<0·001). Health-care workers working on dedicated COVID-19 wards (95 [7·19%] of 1321) had a significantly higher seroprevalence than other frontline health-care workers working in hospitals (696 [4·35%] of 15 983; RR 1·65 [1·34-2·03]; p<0·001). 622 [53·5%] of 1163 seropositive participants reported symptoms attributable to SARS-CoV-2. Loss of taste or smell was the symptom that was most strongly associated with seropositivity (377 [32·39%] of 1164 participants with this symptom were seropositive vs 786 [2·84%] of 27 628 without this symptom; RR 11·38 [10·22-12·68]). The study is registered at ClinicalTrials.gov, NCT04346186.

Interpretation: The prevalence of health-care workers with antibodies against SARS-CoV-2 was low but higher than in blood donors. The risk of SARS-CoV-2 infection in health-care workers was related to exposure to infected patients. More than half of seropositive health-care workers reported symptoms attributable to COVID-19.

Funding: Lundbeck Foundation.

Copyright © 2020 Elsevier Ltd. All rights reserved.

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Seroprevalence according to job assignment…

Seroprevalence according to job assignment compared with blood donors Purple indicates blood donors…

Seroprevalence according to job assignment compared with blood donors Purple indicates blood donors serving as a proxy for the general population (n=4672). Blue indicates health-care workers not working on dedicated COVID-19 wards or frontline (n=11 488). Red indicates frontline health-care workers not working on dedicated COVID-19 wards (n=15 983). Green indicates health-care workers working on dedicated COVID-19 wards (n=1321). NS=not significant.

Seroprevalence stratified according to specialty…

Seroprevalence stratified according to specialty for doctors, nurses, and assisting nurses Figure shows…

Seroprevalence stratified according to specialty for doctors, nurses, and assisting nurses Figure shows specialties with at least 100 participants.

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  Iversen K, Kristensen JH, Hasselbalch RB, Pries-Heje M, Nielsen PB, Knudsen AD, Fogh K, Norsk JB, Andersen O, Fischer TK, Juul Jensen CA, Torp-Pedersen C, Rungby J, Ditlev SB, Hageman I, Møgelvang R, Gybel-Brask M, Dessau RB, Sørensen E, Harritshøj L, Folke F, Sten C, Engel Møller ME, Benfield T, Ullum H, Jørgensen CS, Erikstrup C, Ostrowski SR, Nielsen SD, Bundgaard H. Iversen K, et al. Clin Microbiol Infect. 2022 May;28(5):710-717. doi: 10.1016/j.cmi.2021.09.005. Epub 2021 Sep 17. Clin Microbiol Infect. 2022. PMID: 34543759 Free PMC article.

• Seroprevalence of SARS-CoV-2 antibodies in people with an acute loss in their sense of smell and/or taste in a community-based population in London, UK: An observational cohort study.

  Makaronidis J, Mok J, Balogun N, Magee CG, Omar RZ, Carnemolla A, Batterham RL. Makaronidis J, et al. PLoS Med. 2020 Oct 1;17(10):e1003358. doi: 10.1371/journal.pmed.1003358. eCollection 2020 Oct. PLoS Med. 2020. PMID: 33001967 Free PMC article.

• SARS-CoV-2 antibody seroprevalence in the general population and high-risk occupational groups across 18 cities in Iran: a population-based cross-sectional study.

  Poustchi H, Darvishian M, Mohammadi Z, Shayanrad A, Delavari A, Bahadorimonfared A, Eslami S, Javanmard SH, Shakiba E, Somi MH, Emami A, Saki N, Hormati A, Ansari-Moghaddam A, Saeedi M, Ghasemi-Kebria F, Mohebbi I, Mansour-Ghanaei F, Karami M, Sharifi H, Pourfarzi F, Veisi N, Ghadimi R, Eghtesad S, Niavarani A, Ali Asgari A, Sadeghi A, Sorouri M, Anushiravani A, Amani M, Kaveh S, Feizesani A, Tabarsi P, Keyvani H, Markarian M, Shafighian F, Sima A, Sadjadi A, Radmard AR, Mokdad AH, Sharafkhah M, Malekzadeh R. Poustchi H, et al. Lancet Infect Dis. 2021 Apr;21(4):473-481. doi: 10.1016/S1473-3099(20)30858-6. Epub 2020 Dec 15. Lancet Infect Dis. 2021. PMID: 33338441 Free PMC article.

• Seroprevalence of SARS-CoV-2-specific antibodies in cancer outpatients in Madrid (Spain): A single center, prospective, cohort study and a review of available data.

  Cabezón-Gutiérrez L, Custodio-Cabello S, Palka-Kotlowska M, Oliveros-Acebes E, García-Navarro MJ, Khosravi-Shahi P. Cabezón-Gutiérrez L, et al. Cancer Treat Rev. 2020 Nov;90:102102. doi: 10.1016/j.ctrv.2020.102102. Epub 2020 Sep 1. Cancer Treat Rev. 2020. PMID: 32947121 Free PMC article. Review.

• SARS-CoV-2 Prevalence in Malawi Based on Data from Survey of Communities and Health Workers in 5 High-Burden Districts, October 2020.

  Theu JA, Kabaghe AN, Bello G, Chitsa-Banda E, Kagoli M, Auld A, Mkungudza J, O'Malley G, Bangara FF, Peacocke EF, Babaye Y, Ng'ambi W, Saussier C, MacLachlan E, Chapotera G, Phiri MD, Kim E, Chiwaula M, Payne D, Wadonda-Kabondo N, Chauma-Mwale A, Divala TH; Public Health Institute of Malawi COVID-19 surveillance committee3. Theu JA, et al. Emerg Infect Dis. 2022 Dec;28(13):S76-S84. doi: 10.3201/eid2813.212348. Emerg Infect Dis. 2022. PMID: 36502413 Free PMC article. Review.

• SARS-CoV-2 Seroprevalence among Health Care Workers-A Voluntary Screening Study in a Regional Medical Center in Southern Germany.

  Müller K, Girl P, Ruhnke M, Spranger M, Kaier K, von Buttlar H, Dobler G, Borde JP. Müller K, et al. Int J Environ Res Public Health. 2021 Apr 8;18(8):3910. doi: 10.3390/ijerph18083910. Int J Environ Res Public Health. 2021. PMID: 33917840 Free PMC article.

• [Scale of Concern about COVID-19 Infection in Peruvian Health Care Workers].

  Esteban-Carranza RF, Mamani-Benito OJ, Rodriguez-Alarcon JF, Corrales-Reyes IE, Farfán-Solís R. Esteban-Carranza RF, et al. Rev Colomb Psiquiatr. 2023 Jan-Mar;52(1):38-44. doi: 10.1016/j.rcp.2021.03.006. Epub 2021 Apr 28. Rev Colomb Psiquiatr. 2023. PMID: 33994584 Free PMC article. Spanish.

• Seroprevalence of SARS-CoV-2 antibodies, associated epidemiological factors and antibody kinetics among healthcare workers in Connecticut.

  Papasavas P, Olugbile S, Wu U, Robinson K, Roberts AL, O'Sullivan DM, McLaughlin T, Mather JF, Steinberg AC, Orlando R, Kumar A. Papasavas P, et al. J Hosp Infect. 2021 Aug;114:117-125. doi: 10.1016/j.jhin.2021.04.021. Epub 2021 Apr 27. J Hosp Infect. 2021. PMID: 33930487 Free PMC article.

• Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence Survey Among 17 971 Healthcare and Administrative Personnel at Hospitals, Prehospital Services, and Specialist Practitioners in the Central Denmark Region.

  Jespersen S, Mikkelsen S, Greve T, Kaspersen KA, Tolstrup M, Boldsen JK, Redder JD, Nielsen K, Abildgaard AM, Kolstad HA, Østergaard L, Thomsen MK, Møller HJ, Erikstrup C. Jespersen S, et al. Clin Infect Dis. 2021 Nov 2;73(9):e2853-e2860. doi: 10.1093/cid/ciaa1471. Clin Infect Dis. 2021. PMID: 33011792 Free PMC article.

• COVID-19 among workers of a comprehensive cancer centre between first and second epidemic waves (2020): a seroprevalence study in Catalonia, Spain.

  Peremiquel-Trillas P, Saura-Lázaro A, Benavente-Moreno Y, Casabonne D, Loureiro E, Cabrera S, Duran A, Garrote L, Brao I, Trelis J, Galán M, Soler F, Julià J, Cortasa D, Domínguez MÁ, Albasanz-Puig A, Gudiol C, Ramírez-Tarruella D, Muniesa J, Rivas JP, Muñoz-Montplet C, Sedano A, Plans À, Calvo-Cerrada B, Calle C, Clopés A, Carnicer-Pont D, Alemany L, Fernández E. Peremiquel-Trillas P, et al. BMJ Open. 2022 Apr 21;12(4):e056637. doi: 10.1136/bmjopen-2021-056637. BMJ Open. 2022. PMID: 35450905 Free PMC article.

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